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Hormones, Metabolism and the Benefits of Exercise
The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
Research Grants
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Dietary Fat and Cancer
The annual research conference for 1996 of the American Institute for Cancer Re search was again held at the Loews L'Enfant Plaza Hotel in Washington, DC, August 29 and 30. The topic for this, the seventh in the series, was "Dietary Fat and Cancer: Genetic and Molecular Mechanisms. " Two separate presentations were given as the conference overview. "Fat and Cancer: The Epidemiologic Evidence in Perspective" noted that die tary fat can be saturated, largely from animal or dairy sources, or mono- or polyunsatu rated, mostly from plant sources. Unlike animal fats, fish contain relatively high levels of protective omega-3 fatty acids. Although the hypothesis that dietary fat is associated with c...
The Genetics of Health
"SHARAD P. PAUL, MD, is starting a health RxEvolution. He argues it's time to stop relying on prescriptive drugs to alleviate all ailments and instead take charge of your own life wellness. He walks readers through the genes that are key to our physical and mental fitness and longevity, the genesis of those genes, and how actions play a role in the expression of genes in our bodies. Each chapter concludes with practical and easily implemented actions that help readers start managing their daily wellbeing and encourages them to personalize his steps for their own bodies and lifestyles. Dr. Paul has been recognized for his thought leadership, compassion, and entrepreneurialism. In addition to his busy skin surgery schedule, he offers 7,000 free skin cancer checks every year and even invented a skin graft technique that reduces costs and healing time for patients. With The Genetics of Health, he offers the knowledge and the guidance for readers to personally take charge of reducing their own healthcare costs and sick days, and to seize the healthiest life possible"--
Biosimilars of Monoclonal Antibodies
Addressing a significant need by describing the science and process involved to develop biosimilars of monoclonal antibody (mAb) drugs, this book covers all aspects of biosimilar development: preclinical, clinical, regulatory, manufacturing. • Guides readers through the complex landscape involved with developing biosimilar versions of monoclonal antibody (mAb) drugs • Features flow charts, tables, and figures that clearly illustrate processes and makes the book comprehensible and accessible • Includes a review of FDA-approved mAb drugs as a quick reference to facts and useful information • Examines new technologies and strategies for improving biosimilar mAbs
Exercise Is Medicine
Aging, despite its dismal reputation, is actually one of the great mysteries of the universe. Why don't we just reproduce, then exit fast, like salmon? Could aging just be one big evolutionary accident? Is senescence, the gradual falling apart of our bodies, at least partially avoidable? Can we extend the healthy lifespan and reduce the lingering, debilitating effects of senescence? In this book, investigative health journalist Judy Foreman suggests that we actually can, and the key element is exercise, through its myriad effects on dozens of molecules in the brain, the muscles, and other organs. It's no secret, of course, that exercise is good for you and that exercise can extend longevity....
Molecular Exercise Physiology
Fully revised and expanded, the second edition of Molecular Exercise Physiology offers a student-friendly introduction. It introduces a history documenting the emergence of molecular biology techniques to investigate exercise physiology, the methodology used, exercise genetics and epigenetics, and the molecular mechanisms that lead to adaptation after different types of exercise, with explicit links to outcomes in sport performance, nutrition, physical activity and clinical exercise. Structured around key topics in sport and exercise science and featuring contributions from pioneering scientists, such as Nobel Prize winners, this edition includes new chapters based on cutting-edge research i...
Oncogenes
The second edition of this authoritative text details major advances and developments in the field, such as the identification of many new tumor suppressor genes and the striking progress in understanding signal transduction pathways leading to cell proliferation. Oncogenes, Second Edition, addresses the needs of advanced undergraduates, graduate students, medical students, physicians, and scientists by examining the current state of oncogene study and where future research may lead.
