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Bridging the Gap Before and After Birth: Methods and Technologies to Explore the Functional Neural Development in Humans
Infant brain damage is a serious condition that affects millions of babies each year. The period from late gestation to the first year of life is the most critical one for the development of central and autonomous nervous systems. Medical conditions such as preterm birth may compromise brain function and the end result usually is that the baby may experience long-term neurological problems related to a wide range of psychological, physical and functional complications, with consequent life-long burdens for the individuals and their families, and a high socio-economic impact for the health care system and the whole of society. During the last years, several techniques have been employed to mo...
The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
An essential, up-to-date textbook for postgraduate trainees preparing for the EBCOG Fellowship exam.
Breast Cancer: Global Quality Care
Developing or existing breast cancer centres strive to provide the highest quality care possible within their current financial and personnel resources. Written by a team of over 100 experts from 25 countries, this book provides a practical and comprehensive guide to delivering high quality breast cancer care wherever you live.
Treatment Strategies and Survival Outcomes in Breast Cancer
Treatment strategies for breast cancer are wide-ranging and often based on a multi-modality approach, depending on the stage and biology of the tumour and the acceptance and tolerance of the patient. They may include surgery, radiotherapy, and systemic therapy (endocrine therapy, chemotherapy, and targeted therapy). Advances in technologies such as oncoplastic surgery, radiation planning and delivery, and genomics, and the development of novel systemic therapy agents alongside their evaluation in ongoing clinical trials continue to strive for improvements in outcomes. In this Special Issue, we publish a collection of studies looking at all forms of therapeutic strategies for early and advanced breast cancer, focusing on their outcomes, notably survival.
Oncolytic Virotherapy
Using viruses to treat cancer is an established concept, and many viruses have shown promising anti-tumor efficacies. Oncolytic viruses are safe and well-characterized pathogens with a stable genome. The outstanding clinical results for oncolytic virotherapy deserve serious attention and consideration to make it a treatment option alongside classical cancer therapeutics. Virotherapy uses replication-competent oncolytic viruses to replicate and destroy cancer cells selectively. The transformed nature of cancer cells offers a permissive environment for some viruses’ replication and to complement viral mutations. The in situ amplification and spread within the tumor mass is the key benefit of such replication-competent viruses. Oncolytic virotherapy is divided into two main groups, according to tumor specificity: naturally oncolytic viruses to replicate in human cancer cells; and gene-modified viruses engineered to accomplish selective oncolysis.
Atlas of Gynecologic Surgery
A groundwork and milestone for an innovative, trendsetting, and international school of thought in gynecology. A superb work of art as well as an outstanding clinical reference, this book continues the rich tradition of earlier editions by providing unparalleled coverage of the entire field of gynecologic surgery. This new fourth edition offers completely updated content, user-friendly features, and the cornerstone of the book: an art program of astounding quality. It is indispensable for gynecologic surgeons or residents who need to review, refresh, or fine-tune their skills in preparation for surgery, while being alerted to pitfalls and possible complications at every juncture. Special fea...
Living Donor Organ Transplantation
Living Organ Donor Transplantation, Second Edition puts the entire discipline in perspective while guiding readers step-by-step through the most common organ transplant surgeries. Organized into four cohesive parts and featuring numerous surgical illustrations, this sourcebook delivers an incisive look at every key consideration for general surgeons who perform transplantations, from patient selection to recipient workup and outcomes, and emphasizes the most humanitarian approaches. Sections provide content on living donor uterus transplantation, new operative techniques, including the use of robotic and minimally invasive transplant procedures, new immunosuppressive regimens, new protocols ...
