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This book is an up-to-date, comprehensive review of the neuropsychiatry of multiple sclerosis and related diseases, by active authorities in the field, with an emphasis on diagnosis and management. Critical appraisal of the methodological aspects and limitations of the current research on the neuropsychiatry of demyelinating diseases is included, and unanswered questions are highlighted. Pharmacological aspects of management are discussed. Neuropsychiatric Symptoms of Inflammatory Demyelinating Diseases is aimed at neurologists, multiple sclerosis specialists and psychiatrists, and will also be of interest to intensive care doctors, psychologists ad neuropsychologists, research and specialist nurses, clinical researchers and methodologists.
2004 BMA Medical Book Competition Winner (Radiology category) “This is an exciting book, with a new approach to use of the MRI scanner. It bridges the gap between clinical research and general neuro-radiological practice. It is accessible to the clinical radiologist, and yet thorough in its treatment of the underlying physics and of the science of measurement. It is likely to become a classic.” British Medical Association This indispensable 'how to' manual of quantitative MR is essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological disease, its progression, and its response to treatment. It contains both the methodology and c...
In the past few years there have been impressive advances in the implementation of modern MRI techniques for the assessment of MS patients with the ultimate goal to define MRI markers of MS evolution. The authors of this volume not only review these new techniques, such as magnetization transfer (MT) MRI, diffusion-weighted (DW) MRI and proton MR spectroscopy (MRS), that are increasingly being used to monitor MS evolution, but also those, such as functional MRI (fMRI), cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, that are emerging as additional promising tools for improving our understanding of MS pathophysiology. Strengths and weaknesses of all these modern quantitative MRI techniques for the study of MS are extensively covered in this book. The book also provides a valuable summary of the state of the art.
In the last thirty years, Magnetic Resonance has generated a wide revolution in biomedical research and in medical imaging in general. More recently, the "in vivo" studies of the human brain were extended by new original ways to the dynamic study of function and metabolism of the human brain. The enormous interest in expanding the investigation of the brain is emphasizing the search for new NMR methods capable of extracting information of so-far obscure aspects of the brain function. In fact, many quantitative approaches have been proposed in order to complement the information obtained by functional MRI, and several multimodal and multiparametric approaches have been developed to exploit th...
In this issue of Neuroimaging Clinics, guest editors Drs. Frederik Barkhof and Yaou Liu bring their considerable expertise to the topic of Multiple Sclerosis and Associated Demyelinating Disorders. Top experts in the field discuss advanced brain imaging in CNS demyelinating diseases; new imaging markers in MS and related disorders: smoldering inflammation and central vein sign; the use of AI in MS and white matter disease; optic nerve imaging in MS and related disorders; atypical demyelinating disorders; and more. Co-Editor Frederik Barkhof, MD, has received the National Multiple Sclerosis Society and the American Academy of Neurology’s 2018 John Dystel Prize for Multiple Sclerosis Researc...
We would like to acknowledge that Dr. Monica Margoni, University of Padua, Italy, has acted as a coordinator and has contributed to the preparation of the proposal for this Research Topic.
La sclérose en plaques est une affection neurologique handicapante qui peut atteindre les individus de tous âges. Elle se caractérise par des atteintes multifocales et diffuses du système nerveux entraînant de nombreuses affections. Cette maladie, complexe en termes d’étiologie, de diagnostic clinique et de sémiologie, est difficile à prendre en charge d’un point de vue thérapeutique. Cet ouvrage, consacré aux aspects cliniques et thérapeutiques de la sclérose en plaques , rend compte des récentes avancées en termes de diagnostic et de prise en charge des patients et permet au praticien de mieux appréhender cette maladie. Le chapitre 1 décrit tous les signes et symptômes...
Les symptômes de la sclérose en plaques altèrent profondément la qualité de vie des malades. Une prise en charge spécifique et un soutien important de l’entourage sont nécessaires. Cet ouvrage inédit offre aux malades et à leurs proches une source précieuse de conseils et témoignages de patients experts de la LFSEP et expose les principales caractéristiques de la maladie. Il propose des informations pratiques, des réponses aux questions et aux idées reçues, une vision plus réaliste de la maladie et de son évolution et les approches thérapeutiques disponibles. L’intégralité des droits d’auteurs sera reversée à la Ligue française contre la sclérose en plaques.