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Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development. For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.
1. Type 3 Diabetes Mellitus: How Relevant in Clinical Practice? 2. The Dirty Dozen of Diabetes 3. Studying Genomics of Diabetes: Now a Useful Tool for Physicians 4. Hypogonadotropic Hypogonadism in Men with Type 2 Diabetes Mellitus 5. Ramadan Fasting for Patients with Diabetes Mellitus: Implications and Suggestions for Management 6. Antidiabetic Drugs of Next Decade 7. Siphoning Blood Glucose: A Novel Therapy 8. Type 2 Diabetes Mellitus and Gut Microbiota 9. Microvascular and Macrovascular Complications in Diabetes Mellitus: Distinct or Continuum? 10. Technological Advances in Type 1 Diabetes Mellitus Therapy 11. Role of Nanotechnology in Diabetes Management 12. Bionic Pancreas Index