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In the global war to control tuberculosis (TB), there are several critical battles which must be waged and won if we are to make significant progress. Broadly speaking, these battlefields may be regarded as diagnosis, treatment and prevention. Within the arena of treatment are various critical elements. Current drug regimens require 6 months to achieve predictable cures; it is essential that shorter regimens be developed to lessen non-adherence and to improve affordability. To facilitate directly-observed therapy, intermittent (less than daily) regimens have been employed. To ensure favourable outcomes, including patients with AIDS, thrice-weekly regimens are the current standard; reducing t...
Over three previous editions, Clinical Tuberculosis has established itself as an indispensable guide to all aspects of tuberculosis diagnosis and treatment. This fully revised and updated fourth edition provides practical guidance to healthcare professionals involved in any aspect of patient management or disease control; chapters are included on epidemiology, pathology, immunology, disease presentation, diagnosis, treatment and management options. The problem of TB associated with HIV infection is given special emphasis, as are the increasing problems of multi-drug resistant strains and environmentally opportunistic mycobacteria. Chapter authors have been hand-picked to represent the most up-to-date thinking in their particular subject areas, making Clinical Tuberculosis the essential reference work for the bookshelves of respiratory physicians, infectious disease specialists, public health workers and other individuals involved in the management and control of tuberculosis worldwide.
This comprehensive volume provides an update on the current state of pharmacometrics in drug development. It consists of nineteen chapters all written by leading scientists from the pharmaceutical industry, regulatory agencies and academia. After an introduction of the basic pharmacokinetic and pharmacodynamic concepts of pharmacometrics in drug development, the book presents numerous examples of specific applications that utilize pharmacometrics with modeling and simulations over a variety of therapeutic areas, including pediatrics, diabetes, obesity, infections, psychiatrics, Alzheimer’s disease, and dermatology, among others. The examples illustrate how results from all phases of drug d...
The bibliography lists nearly 5,000 compositions by 200 composers of jazz and "art" music, indicating where scores or realizations can be purchased, rented, or borrowed, and which Boston area libraries have them in their collections.
Completely updated and revised, Clinical Tuberculosis continues to provide the TB practitioner-whether in public health, laboratory science or clinical practice-with a synoptic and definitive account of the latest methods of diagnosis, treatment and control of this challenging and debilitating disease.New in the Fifth Edition:Gamma interferon-based
This volume represents the proceedings of the 2013 International Conference on Innovation, Communication and Engineering (ICICE 2013). This conference was organized by the China University of Petroleum (Huadong/East China) and the Taiwanese Institute of Knowledge Innovation, and was held in Qingdao, Shandong, P.R. China, October 26 - November 1, 2013. The conference received 653 submitted papers from 10 countries, of which 214 papers were selected by the committees to be presented at ICICE 2013. The conference provided a unified communication platform for researchers in a wide range of fields from information technology, communication science, and applied mathematics, to computer science, advanced material science, design and engineering. This volume enables interdisciplinary collaboration between science and engineering technologists in academia and industry as well as networking internationally. Consists of a book of abstracts (260 pp.) and a USB flash card with full papers (912 pp.).
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The revised and up-to-date third edition of Drug Interactions in Infectious Diseases delivers a text that will enhance your clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The third edition features five new chapters that cover material not addressed in previous editions. These new chapters describe interactions with a number of drug classes such as non-HIV antiviral, antimalarial, antiparasitic, antihelmintic, macrolide, azalide and ketolide agents. A novel chapter on probe cocktail studies has been included to highlight an important research tool for drug development. These chapters addr...
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This book aims to provide converging evidence as to how knowledge about different categories is represented in the brain, and how this knowledge develops.