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It has been known for over 150 years that hallmarks of inflammation can be observed in the wall of atherosclerotic vessels. It was, however, not clear if this inflammation is the cause or the consequence of atherogenesis. More recently, it has become evident that inflammation mediated both by innate and adaptive immunity is instrumental even in the earliest stages of the development of atherosclerotic lesions, i.e., that it plays an important pathogenetic role. In this volume, international experts in the field discuss the pathogenetic, diagnostic, preventive and possible therapeutic relevance of inflammation in atherogenesis. This book is intended for researchers and physicians in the fields of vascular biology, immunology and atherosclerosis.
Surface engineering provides one of the most important means of engineering product differentiation in terms of quality, performance, and lifecycle cost. It is essential to achieve predetermined functional properties of materials such as mechanical strength, biocompatibility, corrosion resistance, wear resistance, and heat and oxidation resistance. Surface Engineering of Biomaterials addresses this topic across a diverse range of process technologies and healthcare applications. Introduces biomaterial surface science and surface engineering and includes criteria for biomaterial surface selection Focuses on a broad array of materials including metals, ceramics, polymers, alloys, and composites Discusses corrosion, degradation, and material release issues in implant materials Covers various processing routes to develop biomaterial surfaces, including for smart and energy applications Details techniques for post-modification of biomaterial surfaces This reference work helps researchers working at the intersection of materials science and biotechnology to engineer functional biomaterials for a variety of applications.
Increasing evidence suggests that hidden, low-level inflammation may be the number one cause of modern disease. Shilpa Ravella, an expert in nutrition and the gut, explains why our immune systems are turning against us and what we might do about it. 'Controlling inflammation is the key to good health and this beautifully written and researched book is the best way to understand it' TIM SPECTOR, #1 bestselling author of Food for Life 'A beautiful and authoritative dive into one of the most important scientific frontiers of our time' DANIEL M. DAVIS, Professor of Immunology and author of The Beautiful Cure ___ Inflammation is the body's response to injury and foreign microbes. But as our envir...
過敏、心臟病、糖尿病、癌症、失智、憂鬱症…… 數世紀以來,醫者百思不得其解病因。 全美胃腸科名醫暨營養學專家帶我們一步步揭露真相── 發炎既是萬病的警鈴、自癒的援兵,也是致病的源頭; 進而探知人體的免疫機制與逆轉疾病的祕密。 ★TED-Ed醫學科普影片超過600萬次觀看 ★入圍美國2023 Phi Beta Kappa 科學獎 拉維拉的朋友傑伊有一天突然生了怪病,他的頸椎出了問題,無法正常行走,醫生也檢查不出原因。傑伊還很年輕才三十出頭,而且平常身體健康。後來醫生推斷是「重度發炎」。這次經歷讓拉維拉醫師對「發...
"Passionate and meticulous . . . [Ehrlich] delivers thought-provoking metaphors, unforgettable scenes and many beautifully worded phrases." —Benjamin Labatut, The New York Times Book Review One of The Telegraph's best books of the year The first major biography of the Nobel Prize–winning scientist who discovered neurons and transformed our understanding of the human mind—illustrated with his extraordinary anatomical drawings Unless you’re a neuroscientist, Santiago Ramón y Cajal is likely the most important figure in the history of biology you’ve never heard of. Along with Charles Darwin and Louis Pasteur, he ranks among the most brilliant and original biologists of the nineteenth...
Перед вами захватывающее исследование воспаления – скрытой силы, лежащей в основе современных болезней! Гастроэнтеролог Шилпа Равелла раскрывает тайны этого загадочного и скрытого от глаз явления и рассказывает, как воспаление может обернуться против нас, став триггером болезней сердца и рака, депрессии и старения, а также загадочных аутоиммунных состояний.На страницах книги...
It has been known for over 150 years that hallmarks of inflammation can be observed in the wall of atherosclerotic vessels. It was, however, not clear if this inflammation is the cause or the consequence of atherogenesis. More recently, it has become evident that inflammation mediated both by innate and adaptive immunity is instrumental even in the earliest stages of the development of atherosclerotic lesions, i.e., that it plays an important pathogenetic role. In this volume, international experts in the field discuss the pathogenetic, diagnostic, preventive and possible therapeutic relevance of inflammation in atherogenesis. This book is intended for researchers and physicians in the fields of vascular biology, immunology and atherosclerosis.
Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.