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So much has been written about the scientific contributions of Sherrington that the man himself, and his thoughts, have been overshadowed. More and more, students of history are calling for creative writing on the whole man, particularly when he is a genius. Those interested in the genesis of ideas want to know the settings for discoveries and the relevant circumstances which ushered in new truths and new insights. The "prepared mind" which Pasteur saw as the only one to be "favoured by fortune" is of immense importance in science, and our account of Sherring ton, we hope, will fill a very real gap in this field. During his life Sherrington actively discouraged any sugges tions that a biography be written. For that reason it was not until 1947 that there were any biographical notes by John Fulton, Graham Brown and A. D. Ritchie in a number of the British Medical Journal commemorating his ninetieth birthday, and in addition there was a leading article entitled "The Influence of Sherrington on Oinical Neurology". He left no autobiographical material except the few pages of reminiscences entitled "Mar ginalia", an essay written in honour of Charles Singer (1953).
"This selection of extracts and full reprints from the classical papers of Sir Charles Sherrington is designed both as a testimonial to their author and as a source book for those concerned with the problems of reflex physiology ... The subjects dealt with include the innervation of muscles, the pattern of the skin segments, the spinal animal and its reactions, and the development of modern conceptions of reciprocal innervation, reflex posture, inhibition, and cortical localization. Appended to the text there is a complete bibliography of Sheridan's writings." -- Book jacket
This book has been considered by academicians and scholars of great significance and value to literature. This forms a part of the knowledge base for future generations. So that the book is never forgotten we have represented this book in a print format as the same form as it was originally first published. Hence any marks or annotations seen are left intentionally to preserve its true nature.
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The History of the Synapse provides a history of those discoveries concerning the identification and function of synapses that provide the foundations for research during this new century with a personal view of the process by which new concepts have developed. Previously published as essays, the chapters in this book provide a history of various aspects of synaptic function, beginning with the evolution over two and a half thousand years and how progress was made in the establishment of a conceptual structure that would allow the synapse to be identified at the beginning of the 20th century. Numerous illustrations explain either the technical approach or the experimental finding.