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Cancer Stem Cells
An innovative theory proposes a new therapeutic strategy to break the stalemate in the war on cancer. It is called cancer stem cell (CSC) theory, and Lucie Laplane offers a comprehensive analysis, based on an original interdisciplinary approach that combines biology, biomedical history, and philosophy. Rather than treat cancer by aggressively trying to eliminate all cancerous cells—with harmful side effects for patients—CSC theory suggests the possibility of targeting the CSCs, a small fraction of cells that lie at the root of cancers. CSCs are cancer cells that also have the defining properties of stem cells—the abilities to self-renew and to differentiate. According to this theory, o...
Genetics of Cardiovascular Disease
This volume of the esteemed Progress in Molecular Biology and Translational Science series focuses on cutting-edge research related to the genetics of cardiovascular disease. Written by top experts in the field, this volume covers a range of topics, including: - Genetic models of atherosclerosis - MicroRNAs in cardiovascular disease - The role of the transcription factor KLF2 in vascular development and disease - Zebrafish as models of cardiovascular disease and hematopoietic development Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references. - The authors are all experts in the field - The reviews are in themselves comprehensive - Each topic has the potential to lead to advances in therapy of cardiovascular disease
Cellular Dedifferentiation and Regenerative Medicine
This book focuses on the contribution of cell dedifferentiation to the regenerative process in all body systems, as well as its underlying molecular mechanisms and applications. The book is divided into four parts, the first of which addresses the history of cell dedifferentiation and regenerative medicine. In turn, Part II compares three routes by which cells change their phenotype: dedifferentiation, transdifferentiation, and reprogramming. Part III includes an extensive review of cell dedifferentiation events in all nine body systems for lower organisms and mammalians, respectively. The final part reviews the relationship between cell dedifferentiation and the development of cancer and several other diseases, while also outlining the prospects of and future research directions in cell dedifferentiation and regenerative medicine. The main purpose of the book is to underline the importance of cell dedifferentiation in stem cell and regenerative medicine by providing a systematical review of dedifferentiation in all body systems, together with the latest reliable evidence.
Food Processing
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Leading School-based Networks
Based around the lifecycle of a school network, this book takes the reader from the initial inception of a network to considering how to make it sustainable and capable of meeting the future challenges faced by schools and their communities.
Alexander McQueen
"Nick Waplington: Alexander McQueen", Tate Britain exhibition 10 March - 17 May 2015. This major exhibition is the result of a unique collaboration between the artist Nick Waplington (b 1965) and the acclaimed fashion designer Alexander McQueen (1969-2010). In 2009, Waplington was given unprecedented access to McQueen's idiosyncratic creative journey as he prepared his final Autumn/Winter collection, Horn of Plenty. McQueen conceived the Horn of Plenty collection as an iconoclastic retrospective of his career in fashion, reusing silhouettes and fabrics from his earlier collections, and creating a catwalk set out of discarded elements from the sets of his past shows. Their collaboration reveals a raw side of the fashion world, juxtaposing Waplington's candid images of McQueen's intense and theatrical working process with rigorously produced photographs of recycling plants and landfills, creating a powerful commentary on destruction and creative renewal".--Tate website.
Boot Camp
Jay, Summer, Dylan and their bands are headed for boot camp at uber-glamorous Rock War Manor. It's going to be six weeks of mates, music and non-stop partying as they prepare for stardom. But the rock-star life of music festivals and glitzy premieres isn't all it's cracked up to be. Can the bands hold it together long enough to make it through the last stage of the competition, or will there be meltdown? The second book in this spectacular series by the bestselling Robert Muchamore, author of CHERUB.
