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I.e.e.ernesto Alves
Seleção de crônicas que comemoram os Cem anos de vida e história desta Instituição de Ensino
Tertiary Lymphoid Structures
This volume explores the various methods used to study tertiary lymphoid structures (TLS) in pathological situations. Pre-clinical models are also discussed in detail to show how TLS structure, development, and maintenance can be targeted and studied in vivo. The chapters in this book cover topics such as humans and mice; strategies to quantify TLS in order to use it in stained tissue sections; classifying a gene signature form fixed and paraffin-embedded tissues; and development of murine inflammatory models to help look at TLS in the context of infection or malignancy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Tertiary Lymphoid Structures: Methods and Protocols is a valuable resource that increases the reader’s knowledge on immune functions and how they will pave the way to future therapeutic applications.
The Boys Next Door
THE STORY: The place is a communal residence in a New England city, where four mentally handicapped men live under the supervision of an earnest, but increasingly burned out young social worker named Jack. Norman, who works in a doughnut shop and
Man the Hunted
Man the Hunted argues that primates, including the earliest members of the human family, have evolved as the prey of any number of predators, including wild cats and dogs, hyenas, snakes, crocodiles, and even birds. The authors' studies of predators on monkeys and apes are supplemented here with the observations of naturalists in the field and revealing interpretations of the fossil record. Eyewitness accounts of the 'man the hunted' drama being played out even now give vivid evidence of its prehistoric significance. This provocative view of human evolution suggests that countless adaptations that have allowed our species to survive (from larger brains to speech), stem from a considerably more vulnerable position on the food chain than we might like to imagine. The myth of early humans as fearless hunters dominating the earth obscures our origins as just one of many species that had to be cautious, depend on other group members, communicate danger, and come to terms with being merely one cog in the complex cycle of life.
The Making of Modern Colombia
Colombia's status as the fourth largest nation in Latin America and third most populous—as well as its largest exporter of such disparate commodities as emeralds, books, processed cocaine, and cut flowers—makes this, the first history of Colombia written in English, a much-needed book. It tells the remarkable story of a country that has consistently defied modern Latin American stereotypes—a country where military dictators are virtually unknown, where the political left is congenitally weak, and where urbanization and industrialization have spawned no lasting populist movement. There is more to Colombia than the drug trafficking and violence that have recently gripped the world's atte...
Run to Win
From the president of EMILY's List, a playbook for women changing the world in politics, business, or any arena, with a foreword from Vice President Elect Kamala Harris. “I have long believed that women who dream big, work hard, and get back up after they get knocked down can do anything; Stephanie Schriock is one of those women. I’m so glad her thoughtful guidance is now available for women everywhere.”—Hillary Rodham Clinton For the past thirty-five years EMILY's List has helped the campaigns of thousands of pro-choice Democratic women, but the hardest part has always been convincing more women to run. Then Donald Trump was elected, and something shifted into place. American women ...
