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Chemical Safety
How safe is safe enough? We live in a world that is totally dependent on chemicals, be they agrochemicals, pharmaceuticals, colorants - it is vitally important that we adopt a sustainable strategy for an environment containing some 11 million chemicals. This book provides a pragmatic guide to the basic tools of chemical safety assessment, from information retrieval, through hazard and risk assessment to safety evaluation and legal aspects. It is truly global in coverage with contributors drawn from East and West, North and South. It covers natural and artificial hazards to the environment, including the potentially catastrophic effects of modern warfare, and encompasses pollution of air, water and soil as well as occupational exposure to chemicals. Everyone with a professional interest in pollution control will find this an invaluable source of information - chemists, environmental scientists, chemical engineers, political scientists, toxicologists, ecotoxicologists, in industry, academia, government departments and international agencies - all will be guided and challenged by the wealth of knowledge it contains.
Guide to Cytochromes
Cytochromes are coloured iron-containing proteins that transfer electrons during cellular respiration and photosynthesis. The Cytochrome P450 family of enzymes catalyze reactions whereby water-insoluble drugs or metabolites, that would otherwise reach toxic levels in cell membranes, are rendered suitably water-soluble to leave the cell and be excreted in the urine. Due to the extensive nature of this subject, which is an area of intense scientific interest, the field is rapidly advancing and there is a need for new textbooks to keep abreast of the latest developments. The book fulfils that role in providing a fast-track approach for those coming into the P450 field, either at postgraduate le...
Constitutional Rights of Prisoners
This text details critical information on all aspects of prison litigation, including information on trial and appeal, conditions of isolated confinement, access to the courts, parole, right to medical aid and liabilities of prison officials. Highlighted topics include application of the Americans with Disabilities Act to prisons, protection given to HIV-positive inmates, and actions of the Supreme Court and Congress to stem the flow of prison litigation. Part II contains Judicial Decisions Relating to Part I. Part II contains briefs of judicial decisions related to the topics covered in the the text, in order to help the reader learn rule of law as well as the reasoning of the court that guides future court rulings. Appendices include Amendments to the Constitution of the United States of America, related court rulings, and a table of cases.
Guide to Cytochromes
This guide to the structure, function and mechanism of the cytochromes P450 focuses on the role of P450s in xenobiotic metabolism and toxicity. Colour illustrations show how modelling of P450s can rationalize their substrate specificity for the metabolism of both endogenous and exogenous chemicals.
Ships Lewis, Edward
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Similarity Models in Organic Chemistry, Biochemistry, and Related Fields
Since Hammett devised the rho-sigma equation in 1937, the application of similarity models through linear free energy relationships (correlation analysis) has become increasingly important for systematising the quantitative data of organic chemistry and related fields. More than twelve years have elapsed since the last appearance of a multi-author, international monograph on this subject, during which time there have been substantial developments. Sophisticated chemometric techniques, such as principal component analysis, have been added to the basic statistical techniques of simple and multiple regression. The interaction with quantum mechanics, particularly in the form of ab initio molecul...
Child Mental and the Law
The legal aspects of child mental health have changed in recent years, yet many who deal professionally with disturbed children are ill informed about the rights and responsibilities of minors. Child Mental Health and the Law addresses the need for a comprehensive, up-to-date text that describes the evolution of child mental health law and the relevance of the law to the child mental health clinician.
