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Oxidoreduction at the Plasma Membranerelation to Growth and Transport
The concept of general oxidoreductase function at the plasma level is new. Oxidoreduction at the Plasma Membrane: Relation to Growth and Transport provides the first truly comprehensive coverage of the oxidoreduction reactions in plasma membranes and the role that can now be attributed to these enzymes in controlling growth and other cell functions in plants and animals. The book describes the nature and orientation of oxidoreductases in plasma membranes; the stimulation of cell growth by oxidants reacting with transplasma membrane electron transport; changes in enzymes in tumor cells; and the basis of the growth effects and oxidoreductase stimulation of membrane transport in relation to kno...
The Pathobiology of Neoplasia
This book is directed primarily to advanced graduate and medical students, postdoctoral trainees, and established investigators having basic research interests in neoplasia. Its content is based in part on the lecture outlines and selected histopathology laboratory components of an advanced course entitled The Pathobiology of Experimental Animal and Human Neoplasia, developed by me for the Experimental Pathology Curriculum of the Department of Pathology at the Medical College of Virginia. In this regard, an effort has been made to integrate pathology with carcinogenesis, genetics, biochemistry, and cellular and molecular biology in order to present a comprehensive and current view of the neo...
ECTO-NOX Proteins
This volume documents this unique family of cell surface proteins. Despite masquerading as intractable and difficult to clone and characterize, ENOX proteins have and continue to offer remarkable opportunities for research, commercial development and outside confirmation of therapeutic, diagnostic and new paradigms to help explain complex biological processes.
Research Grants
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The Golgi Apparatus
The Golgi apparatus (GA) is typically comprised of a series of five to eight cup-shaped, membrane-covered sacs called cisternae that look something like a stack of deflated balloons. The GA is often considered the "distribution and shipping department" for the cell's chemical products. This book traces the first 100 years of GA discovery from the first published accounts from Pavia, Italy, in 1898 to the Centenary Celebration in Pavia, Italy, in 1998 to our most recent discoveries. It summarizes the past 50 years beginning with the modern era of GA discovery, leading up to the present era with almost exclusive focus on molecular biology.
Moral Foods
Moral Foods: The Construction of Nutrition and Health in Modern Asia investigates how foods came to be established as moral entities, how moral food regimes reveal emerging systems of knowledge and enforcement, and how these developments have contributed to new Asian nutritional knowledge regimes. The collection’s focus on cross-cultural and transhistorical comparisons across Asia brings into view a broad spectrum of modern Asia that extends from East Asia, Southeast Asia, to South Asia, as well as into global communities of Western knowledge, practice, and power outside Asia. The first section, “Good Foods,” focuses on how food norms and rules have been established in modern Asia. Ide...
Biosynthesis and Secretion of Milk / Diseases
Lactation: A Comprehensive Treatise, Volume II, Biosynthesis and Secretion of Milk/Diseases, is part of a three-volume treatise containing a total of 28 chapters. The present volume is devoted to the functioning of the mammary gland in the synthesis and secretion of milk. Emphasis has been placed on studies which have described on a biochemical and molecular basis the operation of the pathways and structures involved in the biosynthesis of milk in the functional secretory cells of the mammary gland and the diseases of lactation that can affect them. The volume is organized into two parts. Part I on the biosynthesis of milk covers topics such as the general metabolism associated with the synthesis of milk; biosynthesis of milk fat and milk proteins; biochemistry of lactose and related carbohydrates; and cell structure relating to the formation and secretion of milk. Part II on diseases of the mammary gland and lactation includes studies on the clinical endocrinology of prolactin, microbial diseases of the mammary gland, ketosis, and mouse mammary tumors.
Aqueous Two-Phase Systems
General methodology and apparatus: phase diagrams, preparation and analysis of two-phase systems, partioning and affinity partitioning of macromolecules: Proteins, nucleic acids, studies on protein interactionsmolecular structure, charge, hydrophobicity, and conformational chan ges, partitioning and affinity partitioning of particulates,organellesseparation and subfractionation, menbrane: separation and subfractionation, membrane domain analysis, aqueous phase separation in biologicalsystems, aqueous two-phase systems in large-scale process biotechnolo gy, proteins; downstream processing, design of proteins for enhanced extraction, other applications of aqueous phases in biotechnology. Enzymology.
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