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A disfigured woman discovers a haunted photo album that could make her whole again but only at a terrible price.
This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug discovery pathway. The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and validation area. The lead generation part as a next step focuses on the requirements and technologies to identify new small molecules as lead compounds for further optimization; in a second section the technologies to identify biologics as leads are addressed. The final part focuses on the pharmacological models and technologies to characterize new compounds and the impact of biomarkers to facilitate the transfer of drug candidates into the development phase.
Find more similar titles including a Free Catalog at www.StrongmanBooks.com The story of George F. Jowett is most inspiring to all who are seeking great strength and a powerfully developed body. As a boy he was badly injured and physicians declared he would never live to see the age of fifteen. What the physicians overlooked was the consuming flame of desire which burned within the weak, undersized body. He overcame his physical problems and rose to be one of the world's strongest and best built athletes. The Key to Might and Muscle is his greatest work in the strength field. Tons of information on exercises from head to toe, with many stories of his fellow strongmen and their feats. If you ...
A tale of forbidden love and inevitable death, the medieval legend of Tristan and Isolde recounts the story of two lovers unknowingly drinking a magic potion and ultimately dying in one another's arms. While critics have lauded Wagner's Tristan and Isolde for the originality and subtlety of the music, they have denounced the drama as a "mere trifle"--a rendering of Wagner's forbidden love for Matilde Wesendonck, the wife of a banker who supported him during his exile in Switzerland. Death-Devoted Heart explodes this established interpretation, proving the drama to be more than just a sublimation of the composer's love for Wesendonck or a wistful romantic dream. Scruton boldly attests that Tr...
This guide for programmers teaches how to practice Test Driven Development (TDD), also called Test First Development. Contrary to the accepted approach to testing, when you practice TDD you write tests for code before you write the code being tested. This text provides examples in Java.
Do I believe in the Thirty-Six? I believe in miracles. Sigi had just turned 15 and was living a carefree life in Poland when WWII was declared. Within days, Germany crossed the Polish border and randomly, to assert their intentions, exterminated Jews and Poles. The Siegreich family relocated further into Poland, to Bedzin, hoping the war would pass quickly. It was not to be. Their train enroute to their new home was attacked and they lost many of their belongings, and some friends. Within days of setting up in Bedzin, while out shopping for food Sigi was picked up by German soldiers and taken off with other Polish citizens where he was forced to dig a large trench. The German soldiers then s...
In today's art world many strange, even shocking, things qualify as art. In this book, Cynthia Freeland explains why innovation and controversy are valued in the arts, weaving together philosophy and art theory with many fascinating examples. She discusses blood, beauty, culture, money, museums, sex, and politics, clarifying contemporary and historical accounts of the nature, function, and interpretation of the arts. Freeland also propels us into the future by surveying cutting-edge web sites, along with the latest research on the brain's role in perceiving art. This clear, provocative book engages with the big debates surrounding our responses to art and is an invaluable introduction to anyone interested in thinking about art.
This book reviews nonparametric Bayesian methods and models that have proven useful in the context of data analysis. Rather than providing an encyclopedic review of probability models, the book’s structure follows a data analysis perspective. As such, the chapters are organized by traditional data analysis problems. In selecting specific nonparametric models, simpler and more traditional models are favored over specialized ones. The discussed methods are illustrated with a wealth of examples, including applications ranging from stylized examples to case studies from recent literature. The book also includes an extensive discussion of computational methods and details on their implementation. R code for many examples is included in online software pages.
This book presents contemporary empirical methods in software engineering related to the plurality of research methodologies, human factors, data collection and processing, aggregation and synthesis of evidence, and impact of software engineering research. The individual chapters discuss methods that impact the current evolution of empirical software engineering and form the backbone of future research. Following an introductory chapter that outlines the background of and developments in empirical software engineering over the last 50 years and provides an overview of the subsequent contributions, the remainder of the book is divided into four parts: Study Strategies (including e.g. guidelin...