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Hollywood Incoherent
"Most books about American film in the 1970s tell stories about iconoclastic auteurs working in the shadow of the Vietnam War. Stepping away from this tradition, Todd Berliner gives us a bold and compelling study of the strange, paradoxical narrative style of seventies films, which seemed to flout the canonical structure of the well-made film. Berliner sheds new light on a well-studied period. His lively prose and the delight he takes in explicaring the classics of that era make this book a real pleasure to read."---Stephen Prince, Professor of Cinema at Virginia Tech and author of Firestorm: American Film in the Age of Terrorism "The wave of innovative filmmaking that surged in 1970s Hollyw...
Drug Bioavailability
The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect. The efficacy of drug uptake depends on the one hand on the chemical characteristics of the active substance, above all on its solubility and membrane permeability. On the other hand, it is determined by the organism's ability to absorb pharmaceuticals by way of specific transport proteins or to excrete them. Since many pharmacologically active substances are poorly suited for oral intake, a decisive criterion for the efficacy of a medicine is its so-called bioavailability. Written by an international team from academia and the pharmaceutical indust...
Breaking the Glass Armor
"Classical works have for us become covered with the glassy armor of familiarity," wrote Victor Shklovsky in 1914. Here Kristin Thompson "defamiliarizes" the reader with eleven different films. Developing the technique formulated in her Eisenstein's Ivan the Terrible (Princeton, 1981), she clearly demonstrates the flexibility of the neoformalist approach. She argues that critics often use cut-and-dried methods and choose films that easily fit those methods. Neoformalism, on the other hand, encourages the critic to deal with each film differently and to modify his or her analytical assumptions continually. Thompson's analyses are thus refreshingly varied and revealing, ranging from an ordinar...
New Therapeutic Strategies for Type 2 Diabetes
This book is a state-of-the art review of new therapeutic strategies towards treatments for T2D.
The Purple East
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Statistical Methods in Biomarker and Early Clinical Development
This contributed volume offers a much-needed overview of the statistical methods in early clinical drug and biomarker development. Chapters are written by expert statisticians with extensive experience in the pharmaceutical industry and regulatory agencies. Because of this, the data presented is often accompanied by real world case studies, which will help make examples more tangible for readers. The many applications of statistics in drug development are covered in detail, making this volume a must-have reference. Biomarker development and early clinical development are the two critical areas on which the book focuses. By having the two sections of the book dedicated to each of these topics...
