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Mathematical, Computational and Experimental T Cell Immunology
Mathematical, statistical, and computational methods enable multi-disciplinary approaches that catalyse discovery. Together with experimental methods, they identify key hypotheses, define measurable observables and reconcile disparate results. This volume collects a representative sample of studies in T cell immunology that illustrate the benefits of modelling-experimental collaborations and which have proven valuable or even ground-breaking. Studies include thymic selection, T cell repertoire diversity, T cell homeostasis in health and disease, T cell-mediated immune responses, T cell memory, T cell signalling and analysis of flow cytometry data sets. Contributing authors are leading scientists in the area of experimental, computational, and mathematical immunology. Each chapter includes state-of-the-art and pedagogical content, making this book accessible to readers with limited experience in T cell immunology and/or mathematical and computational modelling.
Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials
Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials. The author introduces a new repeated measures design called S:T design combined with mixed models as a practical and useful framework of parallel group RCT design because of easy handling of missing data and sample size reduction. The book emphasizes practical, rather than theoretical, aspects of statistical analyses and the interpretation of results. It includes chapters in which the author describes some old-fashioned analysis designs that have been in the literature and compares the results with those obtained from the corresponding mixed models. The book will be of interest to biostatisticians, researchers, and graduate students in the medical and health sciences who are involved in clinical trials. Author Website:Data sets and programs used in the book are available at http://www.medstat.jp/downloadrepeatedcrc.html
Big Data Analytics in Oncology with R
Big Data Analytics in Oncology with R serves the analytical approaches for big data analysis. There is huge progressed in advanced computation with R. But there are several technical challenges faced to work with big data. These challenges are with computational aspect and work with fastest way to get computational results. Clinical decision through genomic information and survival outcomes are now unavoidable in cutting-edge oncology research. This book is intended to provide a comprehensive text to work with some recent development in the area. Features: Covers gene expression data analysis using R and survival analysis using R Includes bayesian in survival-gene expression analysis Discusses competing-gene expression analysis using R Covers Bayesian on survival with omics data This book is aimed primarily at graduates and researchers studying survival analysis or statistical methods in genetics.
The Greening of Everyday Life
This interdisciplinary volume develops a distinctive new way of talking about environmental concerns in post-industrial society.
Aluminium and Alzheimer's Disease
The subject of aluminium and Alzheimer's disease has been plagued with controversy. This controversy has served to obscure much of the scientific research in this field, and subsequently has obscured the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease. This book brings together many of the world's leading scientists researching aluminium and life and contains their critical summaries on the known facts about aluminium toxicity in man and to offer an opinion on the implications of this knowledge on a link between aluminium and Alzheimer's disease. The subject areas of the chapters were chosen to reflect the myriad of ways that aluminium is known to ...
Reach Your Goals Without Stressing Out
If you're tired of working hard instead of working smart, if you feel stressed out and fear burnout, this is the book you've been waiting for. Combining the latest brain science with practical mindfulness-based techniques, it takes you on a journey of self-discovery, leading to practical strategies for sustainable, fulfilling success.
The History of the International Biometric Society
The International Biometric Society (IBS) was formed at the First International Biometric Conference at Woods Hole on September 6, 1947. The History of the International Biometric Society presents a deep dive into the voluminous archival records, with primary focus on IBS’s first fifty years. It contains numerous photos and extracts from the archival materials, and features many photos of important leaders who served IBS across the decades. Features: Describes events leading up to and at Woods Hole on September 6, 1947 that led to the formation of IBS Outlines key markers that shaped IBS after the 1947 formation through to the modern day Describes the regional and national group structure,...
Adventures in Financial Data Science
Graham Giller is one of Wall Street's original data scientists. Starting his career at Morgan Stanley in the UK, he was an early member of Peter Muller's famous PDT group and went on to run his own investment firm. He was Bloomberg LP's original data science hire and set up the data science team in the Global Data division there. He them moved to J.P. Morgan to take the role of Chief Data Scientist, New Product Development, and was subsequently Head of Data Science Research at J.P. Morgan and Head of Primary Research at Deutsche Bank. This book is briefly a biography but mostly a narrative of Graham's research in the fields of financial, economic, and alternative data. It contains extensive ...
Stone Medicine
A comprehensive manual for using crystals, gems, and stones to address physical, emotional, and spiritual health conditions • Includes an extensive Materia Medica detailing the healing and spiritual properties of 200 crystals and stones based on Classical Chinese Medicine • Explores the role played by the color of each stone, its Yin and Yang qualities, crystalline structure, chemical composition, and topical and internal applications • Explains how to make stone and crystal elixirs, wear stones as healing jewelry, use them in massage and energy work, and cleanse and recharge them • Based on the oral teachings of Dr. Jeffrey C. Yuen, a Taoist priest from the ancient lineage of the Ja...
