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Known worldwide, chronic kidney disease (CKD) is a disease that affects up to 4% of the population with increasing figures also in the developing countries. Life expectancy of patients affected by CKD is shortened compared to the overall population, and only a minority of patients reach end-stage renal disease (ESRD) with the need for dialysis or renal transplantation; death overtakes dialysis. In the 13 chapters, this book sheds light on the different aspects related to pathophysiology and clinical aspects of CKD, providing interesting insights into not only inflammation and cardiovascular risk but also the interplay of hormones and the functional aspects of endothelial function. In addition, chapters dealing with genetic aspects of polycystic kidney disease and also the clinical handling of patients with CKD and peritoneal dialysis will be beneficial for the open-minded reader.
National and global security can be assessed in many ways but one underlying factor for all humanity is access to reliable sources of water for drinking, sanitation, food production and manufacturing industry. In many parts of the world, population growth and an escalating demand for water already threaten the sustainable management of available water supplies. Global warming, climate change and rising sea level are expected to intensify the resource sustainability issue in many water-stressed regions of the world by reducing the annual supply of renewable fresh water and promoting the intrusion of saline water into aquifers along sea coasts, where 50% of the global population reside. Pro-ac...
These proceedings contain research papers that were accepted for presentation at the 14th International Conference Inter-Eng 2020 ,Interdisciplinarity in Engineering, which was held on 8–9 October 2020, in Târgu Mureș, Romania. It is a leading international professional and scientific forum for engineers and scientists to present research works, contributions, and recent developments, as well as current practices in engineering, which is falling into a tradition of important scientific events occurring at Faculty of Engineering and Information Technology in the George Emil Palade University of Medicine, Pharmacy Science, and Technology of Târgu Mures, Romania. The Inter-Eng conference s...
The key contributions of this conference focused on “3D Printing Multifunctional Materials and Advanced Composites”, “From 3D Printing to Biomedical Applications, ”Ultraprecision Machining of Freeform Surfaced Components and Devices”, “Nanoparticle-Enhanced Fluids” and “Manufacturing Computationally Designed Wearables via 3D Printing”. Keywords: Carbon Fibre Reinforced Thermoplastic, 3D Printing, Laser Melting in a Powder Layer, TiO₂-ABS Composite Filaments, Cutting Tools, Spinning Tool, Cold Plastic Deformation, Ideas Diagram Method, Surface Roughness, Automatic Real-Time Detection, Electrochemical Discharge Drilling, Digital Twins, Metallised Plastic Products, Milling Process, Tube Extrusion, Shear Banding, Laser Machining, Mutually Intersecting Surfaces, ZnMg-Y Biodegradable Alloy, Deep Cryogenic Treatment, Recycled Carbon Fibre, Incremental Deformation, Wear Resistance of Surface Layers, Artificial Intelligence, Digital Modeling, Pressure Pipe, Smart Manufacturing, Noise Reduction, 3D Visualization.
Because genetic factors can impact immune responses, and immunogenetic associations serve as a predictor of disease development and as a biological indicator of disease progression, the study of immunogenetics is important to basic genetics and immunology, as well as to translational and individualized medicine.This book addresses a few but important issues on the subject of immunogenetics. First, it will review the role that human leukocyte antigen molecules play in the immune system and then take into consideration the effectiveness of Western blotting for the detection of immunologic proteins. The book will discuss studies on the immunogenetics of cancer and tuberculosis followed by implications for immunotherapy. Working separately, the book will also provide evidence that the application of immunogenetics has improved our understanding of brain and behavior disorders.
This book contains selected papers from International Symposium for Production Research 2022, held on October 6–9, 2022, Turkey. The book reports recent advances in production engineering and operations. It explores topics including: production research; production management; operations management; industry 4.0; industrial engineering; mechanical engineering; engineering management; and operational research. Presenting real-life applications, case studies, and mathematical models, this book is of interest to researchers, academics, and practitioners in the field of production and operation engineering. It provides both the results of recent research and practical solutions to real-world problems.
This publication is a product of the project ‘CHASING STORIES MB’ coordinated by Yusuf ÖZCAN and Helena LOURENÇO in 2021-2022. Bu kitap 2019-2020 yıllarında Yusuf ÖZCAN ve Helena LOURENÇO tarafından yürütülen ‘CHASING STORIES projesinin ürünüdür. Editor Editör : Ahmet ARSLAN Translation Editor Çeviri Editörü : Neşe Marmara OZAN Book Design Dizgi-Mizanpaj : Yusuf ÖZCAN Front Cover Painting: Arif (Necip Fazıl Kısakürek İHL) Copyright © 2022, Ahmet ARSLAN All rights reserved. First edition, April 2022
The scientific advances in life sciences and engineering are constantly challenging, expanding, and redefining concepts related to the biocompatibility and safety of medical devices. New biomaterials, new products, and new testing regimes are being introduced to scientific research practices. In order to provide clinically predictive results and to ensure a high benefit–risk ratio for patients, we need to optimize material and implant characteristics, and to adapt performance and safety evaluation practices for these innovative medical devices. Various characteristics related to materials and implant development such as raw materials composition, implant surface morphology, design, geometr...