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Bioorganic and Medicinal Chemistry of Fluorine
Provides a thorough overview of the role of fluorine in pharmaceutical science and development Includes chapters on fluorinated analogues of natural products, fluorinated amino acids and peptides, and derivatives of sugars Classifies marketed and in-development fluorinated pharmaceuticals according to their therapeutic classes
Fluorine and Health
Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and...
Biomedical Frontiers of Fluorine Chemistry
Developed from symposia sponsored by the Division of Fluorine Chemistry and the Division of Medicinal Chemistry.
Fluorine in Medicinal Chemistry and Chemical Biology
The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development. Focusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospect...
Fluorine-Containing Reagents
Another hot-topic volume in the Handbook of Reagents for Organic Synthesis series! This is the first book with all relevant Fluorine containing reagents, and it is an important addition to the vast list of existing books on organic and inorganic Fluorine synthesis. Synthetic chemists, most particularly medicinal and pharmaceutical chemists, are often called upon to prepare compounds that contain Fluorine as a key structural feature. In the past, this seemed to be a domain for specialists, today every synthetic chemist working in these area is expected to synthesize compounds containing Fluorides. This book will be an important source of information for the selection and handling of the right reagents. A must-to-have resource for all synthetic chemists working in drug development and medicinal chemistry Makes use of the leading reagent database e-EROS.
Current Fluoroorganic Chemistry
The book contains 30 top-notch chapter-reviews on recent methodological developments in the area of synthetic fluoro-organic chemistry, Fluorous technology, and biological applications of fluorinated compounds. Special emphases are given to the synthesis of biologically relevant compounds (alcohols, amines, alpha- and beta-amino acids, peptides), industrial-scale production of highly versatile, synthetically useful fluorinated synthons, as well Fluorous technology. The book has been designed to be a comprehensive snap-shot of current research activity in the field reviewed by internationally renowned leading experts from academic and industrial laboratories around the world. The topics cover...
Reagents, Auxiliaries, and Catalysts for C-C Bond Formation
Handbook of Reagents for Organic Synthesis Reagents, Auxiliaries and Catalysts for C-C Bond Formation Robert M. Coates and Scott E. Denmark The University of Illinois, Urbana, USA Recognising the critical need for bringing a handy reference work that deals with the most popular reagents in synthesis to the laboratory of practising organic chemists, the Editors, of the acclaimed Encyclopedia of Reagents for Organic Synthesis (EROS) have selected the most important and useful reagents employed in contemporary organic synthesis. The Handbook of Reagents for Organic Synthesis; Reagents Auxiliaries and Catalysts for C-C Bond Formation, provides practical and concise information on a diverse group...
