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This detailed book brings together a number of state-of-the-art protocols to generate different types of neural cells through the use of reprogramming technologies. Additionally, the volume explores different aspects of functional evaluation and applications of reprogrammed neural cells as well as in silico methods to aid reprogramming efforts. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Neural Reprogramming: Methods and Protocols provides ample experimental experience and guidance for anyone, be it experienced researcher or beginner, to generate, validate, and apply reprogrammed neural cells in their research.
This open access book presents a comprehensive and up-to-date collection of knowledge on the state of crowdfunding research and practice. It considers crowdfunding models and their different manifestations across a variety of geographies and sectors, and explores the perspectives of fundraisers, backers, platforms, and regulators. Gathering insights from a wide range of influential researchers in the field, the book balances concepts, theory, and case studies. Going beyond previous research on crowdfunding, the contributors also investigate issues of community, sustainability, education, and ethics. A vital resource for anyone researching crowdfunding, this book offers readers a deep understanding of the characteristics, business models, user-relations, and behavioural patterns of crowdfunding.
This book covers the complete field of head and neck pathology – from Abscess to Wegener`s Granulomatosis, Sinonasal. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.
This important new textbook offers a lively and topical discussion of how digital technologies impact various aspects of organizations, such as structure, knowledge, collaboration, communication, identity, legitimacy and power. Taking a critical and nuanced approach, this engaging textbook introduces readers to central themes in organization studies and reflects on how changes brought about by digitalization have important implications for private, public and voluntary organizations, and on practical disciples such as strategy, management, innovation and entrepreneurship. Contemporary case studies drawn from a wide range of international organizations demonstrate the real-world relationship between digital technologies and organizing. This is an essential textbook for final year undergraduates, postgraduates and MBA students taking a module in technology and organization. It is also suitable for any student of organizational studies wanting to understand more about the role that the digital plays in contemporary organizing.
This is a practical introduction to the techniques of neural transplantation in mammalian brain tissue. It provides a detailed description of the techniques, written by acknowledged experts in the field, with practical details and hints complementing the underlying principles. Each chapter identifies the equipment needed, the preparations to be made in advance, and step-by-step protocols for each procedure. All aspects of neural transplantation surgery are covered, from staging and dissection of embryonic CNS tissues, through the preparation of tissues for implantation, to the transplant surgery itself. A variety of different methods for solid and cell suspension transplantation are covered....
"Flow Chemistry fills the gap in graduate education by covering chemistry and reaction principles along with current practice, including examples of relevant commercial reaction, separation, automation, and analytical equipment. The Editors of Flow Chemistry are commended for having taken the initiative to bring together experts from the field to provide a comprehensive treatment of fundamental and practical considerations underlying flow chemistry. It promises to become a useful study text and as well as reference for the graduate students and practitioners of flow chemistry." Professor Klavs Jensen Massachusetts Institute of Technology, USA Broader theoretical insight in driving a chemical reaction automatically opens the window towards new technologies particularly to flow chemistry. This emerging concept promotes the transformation of present day's organic processes into a more rapid continuous set of synthesis operations, more compatible with the envisioned sustainable world. These two volumes Fundamentals and Applications provide both the theoretical foundation as well as the practical aspects.
This book presents state-of-the-art pre-clinical models and clinical applications of stem-cell-based therapies applied to different lung diseases, with a special focus on the translation of bench data into clinical studies. Starting with the assumption that abnormal lung tissue repair and regeneration has emerged as the driving force underlying pathogenesis and progression in many lung diseases, it sheds new light on the potential of stem/stromal cells as drivers of repair and sources of reparative factors in the lung. The first part of the book offers an overview of stem cell types and mechanisms involved in lung development, homeostasis, repair and regeneration, and reveals the crucial rol...
Advances in Dance/Movement Therapy (DMT) has a truly international scope. Seventeen researchers from five continents present their recent empirical and theoretical work in the field. They cover topics such as work with cancer patients, fibromyalgia patients, dementia patients, victims of domestic violence and trauma, nonverbal parent child interaction, movement analysis of workplace communication, intercultural work, group process, energy dynamics, and theoretical perspectives on body image, medical DMT, embodiment approaches, and affect regulation. The book addresses a broad range of health professionals and anyone interested in DMT. It is suited for teaching graduate student research classes. The Creative Arts Therapies community and also more and more psychologists and medical doctors have been crying out for more research publications in DMT. This book aims to satisfy this gap in the literature.