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Signal Transduction during Biomembrane Fusion begins with three review articles that put the problem of signal transduction and biomembrane fusion into a general perspective. Each subsequent chapter begins with an introduction which reviews past work on a specific biological system. The authors' current research is then detailed. The chapters conclude with final comments wherein the contributors express viewpoints about the general significance and progression of their work. This book comprises 12 chapters, with the first focusing on signal transduction during biomembrane fusion. The succeeding chapters then discuss the ""focal membrane fusion"" model; osmotic phenomena in membrane fusion; c...
First multi-year cumulation covers six years: 1965-70.
Sexual Interactions in Eukaryotic Microbes provides a comprehensive discussion of the sexual processes of eukaryotic microorganisms. The book is organized into three parts. Part I presents an overview of intercellular communication, covering the modes of cellular communication and the benefit of using eukaryotic microbes for studying cell communication. Part II on pheromonal interactions includes studies on the role of sex pheromones in organisms such as Saccharomyces cerevisiae, Allomyces, Volvox, and Neurospora crassa. Part III on cell surface interactions presents studies such as sexual interactions in Saccharomyces cerevisiae; sexual interactions of the cell surface in Paramecium; and the genetics and cellular biology of sexual development in Ustilago violacea. This book will be of value on a multitude of levels: from a general reference text to a source of research ideas. It will appeal to a wide spectrum of readers in a large number of disciplines, but will be particularly useful to cell biologists, microbiologists, protozoologists, and mycologists interested in the study of cellular communication.
This book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells. The goal of this work is to provide special insight into the nucleolus of the past, present and future, as well its regulation, translocation, and biomedical function. A multitude of topics are introduced and discussed in detail, including nucleologenesis, nucleolar architecture, nucleolar targeting, retention, anchoring, translocation, and the relationship between the nucleolus and cancer. This book also brings together work from several different species, from human to Drosophila to Dictyostelium and other eukaryotic microbes. The final chapter summarizes some of the issues brought up in the various chapters with a view to future research. This book supports the continued emergence of the nucleolus as a dynamic intranuclear region that oversees a vast diversity of events.
"The sex imperative - the irresistible impulse to engage in sexual relations - has enabled animals to share their genes and evolve. Maxwell traces the progress of sex from the simple sharing of genes between cells to the elaborate courtship rituals that developed so sperm could merge with egg. In the effort to join sperm and egg, species have developed some astounding and unusual sexual adaptations. As Maxwell vividly describes the sex lives of various creatures, he attests to the resiliency and amazing adaptability of life to its everchanging environment. By focusing on the diversity of animal sexual relationships, Maxwell enables us to question the very basis of sexuality: What is sex? Why...
In this book, we look at the fundamental biology of the human cell from the outside in. While genes and mutations define our cells and how they function, this volume focuses on the biology of the cell rather than on the nuts and bolts of molecular biology. As a result, the book focuses primarily on protein function in normal and diseased states. The volume reveals how cells are constructed and how they are organized so they work effectively. In each case this understanding is related back to what is known about how mutations and foreign agents lead to many common diseases and ailments. The goal is to develop a holistic view of the normal human cell to set the stage for an understanding of it...
This self-help guide takes students from the challenges of first year through to their successful graduation from university. It contains essentially all of the information that a student needs for success. It covers everything from attending lectures and taking effective notes to preparing for and writing tests and exams. It is packed full of valuable advice and step-by-step approaches that will help every student attain the best marks possible. It guides students through issues like effective listening, writing reports and essays, and tackling different types of test questions. It gives advice on how to avoid problems and when they are unavoidable, how to deal with them effectively. Written by a professor with experience teaching at several universities and an MSc graduate who was awarded multiple scholarships, there is insight and guidance in this volume that cannot be matched. In addition to the University calendar and required textbooks, this is the only complete guide a student will need to reach his or her full potential and to graduate with a degree of which they can be proud.
Molecular and Cellular Aspects of Basement Membranes reviews the knowledge about the molecular and cellular aspects of basement membranes. This book focuses on the composition of basement membranes and their organization in extracellular matrices and presents a structural analysis of the various components of the basement membrane. The importance of basement membranes with respect to cell-matrix interactions, differentiation, and pathology is also considered. This text is organized into three sections and is comprised of 20 chapters. It begins with historical perspectives and an overview of the extracellular matrix in general and the basement membrane in particular. The discussion then turns...
Dementia is a brain disorder that seriously affects a person's ability to carry out daily activities. The most common form of dementia among older people is Alzheimer's disease (AD), which involves the parts of the brain that control thought, memory, and language. Age is the most important known risk factor for AD. The number of people with the disease doubles every 5 years beyond age 65. AD is a slow disease, starting with mild memory problems and ending with severe brain damage. The course the disease takes and how fast changes occur vary from person to person. On average, AD patients live from 8 to 10 years after they are diagnosed, though the disease can last for as many as 20 years. Cur...
The thirteenth edition of this classic text continues and further enriches the rich legacy of the previous editions. In a clear and authoritative style, this edition explains the basic principles of physiology while emphasizing their clinical significance in day-to-day medical practice.