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Molecular and Cellular Mechanisms of Synaptopathies: Emerging Synaptic aging-related molecular pathways in Neurological Disorders
  • Language: en
  • Pages: 133

Molecular and Cellular Mechanisms of Synaptopathies: Emerging Synaptic aging-related molecular pathways in Neurological Disorders

Synapses are complex, highly specialized biological structures. Therefore, even slight functional disturbance can lead to disruptive brain disorders. Dysfunction of these structures is associated with a variety of aging-related neurodegenerative conditions, such as Alzheimer's and Parkinson's disease. Most synaptopathies compromise complex signaling pathways by progressively affecting the synaptic protein repertoire. Currently, the treatment of most of these pathologies focuses on the mitigation of symptoms; in consequence, further efforts need to be made to elucidate the common molecular culprit and cellular mechanisms underlying the cause of these severe pathologies to serve as therapeutic...

Quantifying and Controlling the Nano-Architecture of Neuronal Synapses
  • Language: en
  • Pages: 195
Pathological Hyperactivity and Hyperexcitability in the Central Nervous System
  • Language: en
  • Pages: 130
Sulla statistica teorica in generale e su Melchiorre Gioja in particolare
  • Language: it
  • Pages: 156

Sulla statistica teorica in generale e su Melchiorre Gioja in particolare

  • Type: Book
  • -
  • Published: 1879
  • -
  • Publisher: Unknown

None

التطور: ما تزال نظرية في أزمة
  • Language: ar
  • Pages: 400

التطور: ما تزال نظرية في أزمة

يقول دنتون عن كتابه السابق أن هدفه الأساسي فيه كان "إثبات أنّ الطبيعة غير مستمرة في الأساس"، أي أن الحياة ليست نتيجة للتطور التدريجي البطيء. ولا شك أن هذا يسقط الفكرة الداروينية تماما، أما كتابه الجديد، فيأتي بعد تخليه عن مفهوم التكيفية وتبنيه للبنيوية في عالم الأحياء، لأسباب كثيرة، يفيض في شرحها داخل هذا الكتاب. تأثير ذلك على الصراع مع الداروينية خطير. فنحن إن تجاوزنا النقاش حول كاف...

L'origine dell'uomo e La scelta in rapporto col sesso
  • Language: it
  • Pages: 690

L'origine dell'uomo e La scelta in rapporto col sesso

  • Type: Book
  • -
  • Published: 1888
  • -
  • Publisher: Unknown

None

L'origine dell'uomo e la scelta in rapporto col sesso. Ia tr. ital. col consenso dell'autore, del prof. M. Lessona
  • Language: it
  • Pages: 688
Censimento della popolazione del regno d'Italia al 10 febbraio 1901. Vol. I.-[V.] ...
  • Language: it
  • Pages: 1002
Dario Fo and Franca Rame
  • Language: en
  • Pages: 244

Dario Fo and Franca Rame

  • Type: Book
  • -
  • Published: 1989
  • -
  • Publisher: Unknown

None

Censimento della popolazione del regno d'Italia al 10 febraio 1901. Vol. I.-[V.] ...
  • Language: it
  • Pages: 868