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This book provides an overview of skeletal biology from the molecular level to the organ level, including cellular control, interaction and response; adaptive responses to various external stimuli; the interaction of the skeletal system with other metabolic processes in the body; and the effect of various disease processes on the skeleton. The book also includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically modified animal models. - Presents an in-depth overview of skeletal biology from the molecular to the organ level - Offers "refresher" level content for clinicians or researchers outside their areas of expertise - Boasts editors and many chapter authors from Indiana and Purdue Universities, two of the broadest and deepest programs in skeletal biology in the US; other chapter authors include clinician scientists from pharmaceutical companies that apply the basics of bone biology
*Best New Science Fiction for Summer by The Washington Post *A Most-Anticipated book of 2017 by The Millions Everyone else knows the truth about you, now you can know it, too. That’s the slogan. The product: a junky contraption that tattoos personalized revelations on its users’ forearms. It’s an old con, playing on the fear that we are obvious to everybody except ourselves. This particular ad has been circulating New York since the 1960s and it works. But, oddly enough, so might the device... A small stream of city dwellers buy into this cult of the epiphany machine, including Venter Lowood’s parents. This stigma follows them when they move upstate, where Venter can’t avoid the wh...
A New York Times Book Review Editors' Choice "A radiant first novel. . . . [Neon in Daylight] has antecedents in the great novels of the 1970s: Renata Adler’s Speedboat, Elizabeth Hardwick’s Sleepless Nights, Joan Didion’s Play It as It Lays. . . . Precision—of observation, of language—is Hoby’s gift. Her sentences are sleek and tailored. Language molds snugly to thought." —Parul Sehgal, The New York Times New York City in 2012, the sweltering summer before Hurricane Sandy hits. Kate, a young woman newly arrived from England, is staying in a Manhattan apartment while she tries to figure out her future. She has two unfortunate responsibilities during her time in America: to make...
This textbook describes the biomechanics of bone, cartilage, tendons and ligaments. It is rigorous in its approach to the mechanical properties of the skeleton yet it does not neglect the biological properties of skeletal tissue or require mathematics beyond calculus. Time is taken to introduce basic mechanical and biological concepts, and the approaches used for some of the engineering analyses are purposefully limited. The book is an effective bridge between engineering, veterinary, biological and medical disciplines and will be welcomed by students and researchers in biomechanics, orthopedics, physical anthropology, zoology and veterinary science. This book also: Maximizes reader insights into the mechanical properties of bone, fatigue and fracture resistance of bone and mechanical adaptability of the skeleton Illustrates synovial joint mechanics and mechanical properties of ligaments and tendons in an easy-to-understand way Provides exercises at the end of each chapter
Winner of the 2002 John Gilmary Shea Prize and the 2002 Howard R. Marraro Prize of the American Catholic Historical Association. When Saint Francis of Assisi died in 1226, he left behind an order already struggling to maintain its identity. As the Church called upon Franciscans to be bishops, professors, and inquisitors, their style of life began to change. Some in the order lamented this change and insisted on observing the strict poverty practiced by Francis himself. Others were more open to compromise. Over time, this division evolved into a genuine rift, as those who argued for strict poverty were marginalized within the order. In this book, David Burr offers the first comprehensive hist...
When journalist Arthur Hunt's long-ago incestuous affair with his sister comes to light, he pens a memoir in defense of his life that discusses his broken sense of self, his political ideals, and the crumbling state of the American empire.
“The Secret History meets The Price of Salt” (Vogue) in this “equal parts dangerous and delicious” (Entertainment Weekly) novel about queer desire, religious zealotry, and the hunger for transcendence among the members of a cultic chapel choir at a Maine boarding school—and the ambitious, terrifyingly charismatic girl that rules over them. When shy, sensitive Laura Stearns arrives at St. Dunstan’s Academy in Maine, she dreams that life there will echo her favorite novel, All Before Them, the sole surviving piece of writing by Byronic “prep school prophet” (and St. Dunstan’s alum) Sebastian Webster, who died at nineteen, fighting in the Spanish Civil War. She soon finds the ...
A General History of the Burr Family, With a Genealogical Record from 1193 To 1891 by Charles Burr Todd, first published in 1891, is a rare manuscript, the original residing in one of the great libraries of the world. This book is a reproduction of that original, which has been scanned and cleaned by state-of-the-art publishing tools for better readability and enhanced appreciation. Restoration Editors' mission is to bring long out of print manuscripts back to life. Some smudges, annotations or unclear text may still exist, due to permanent damage to the original work. We believe the literary significance of the text justifies offering this reproduction, allowing a new generation to appreciate it.
This book is concerned with sensory cue integration both within and between sensory modalities, and focuses on the emerging way of thinking about cue combination in terms of uncertainty. These probabilistic approaches derive from the realization that our sensors are noisy and moreover are often affected by ambiguity. For example, mechanoreceptor outputs are variable and they cannot distinguish if a perceived force is caused by the weight of an object or by force we are producing ourselves. The probabilistic approaches elaborated in this book aim at formalizing the uncertainty of cues. They describe cue combination as the nervous system's attempt to minimize uncertainty in its estimates and to choose successful actions. Some computational approaches described in the chapters of this book are concerned with the application of such statistical ideas to real-world cue-combination problems. Others ask how uncertainty may be represented in the nervous system and used for cue combination. Importantly, across behavioral, electrophysiological and theoretical approaches, Bayesian statistics is emerging as a common language in which cue-combination problems can be expressed.