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"The treatment goal of antiretroviral therapy is to achieve and maintain an undetectable viral load. Patients on antiretroviral therapy who do not achieve this goal can develop drug resistance to one or more drugs in the regimen. Poor medication adherence is the most likely reason for virologic failure and the development of drug resistance. Development of new drugs and clinical availability of HIV resistance tests has given providers more options for treatment experienced patients with extensive drug resistance. Evaluating patients with extensive drug resistance requires knowledge of previous antiretroviral drug regimens, previous drug resistance tests, and interpretation of those test. Managing treatment experienced patients can be complex and may require consultation with an HIV expert"--
Noted in Annals of Pharmacotherapy
This book is a thorough, practical review of the challenges facing clinicians treating skin microbes and how to combat these therapeutic dilemmas. It expresses the critical public health concern of antimicrobial resistance and shows how microorganisms are developing the ability to halt the progress of antimicrobials like antibiotics, antivirals, and antifungals. Chapters are grouped together in five sections for ease of use. The first three sections of the book convey foundational information on the mechanisms of antibiotics, antivirals, and antifungals resistance, as well as the implications of lack of vaccination. The fourth section then turns to the specifics of drug resistance for protoz...
Prevent, evaluate, and manage diseases that can be acquired in tropical environments and foreign countries with The Travel and Tropical Medicine Manual. This pragmatic, pocket-sized resource equips medical providers with the knowledge they need to offer effective aid, covering key topics in pre- and post-travel medicine, caring for immigrants and refugees, and working in low-resource settings. It's also the perfect source for travelers seeking quick, easy access to the latest travel medicine information. Dynamic images illustrate key concepts for an enhanced visual understanding. Evidence-based treatment recommendations enable you to manage diseases confidently. Pocket-sized format provides access to need-to-know information quickly and easily. Highlights new evidence and content surrounding mental health and traveling. Covers emerging hot topics such as Ebola virus disease, viral hemorrhagic fevers, the role of point-of-care testing in travel medicine, and antibiotic-resistant bacteria in returning travelers and students traveling abroad. Includes an enhanced drug appendix in the back of the book.
The emir of Bukhara used assassin bugs to eat away the flesh of his prisoners. General Ishii Shiro during World War II released hundreds of millions of infected insects across China, ultimately causing more deaths than the atomic bombs dropped on Japan. These are just two of many startling examples found in Six-legged Soldiers, a brilliant portrait of the many weirdly creative, truly frightening, and ultimately powerful ways in which insects have been used as weapons of war, terror, and torture. Beginning in prehistoric times and building toward a near and disturbing future, the reader is taken on a journey of innovation and depravity. Award-winning science writer Jeffrey A. Lockwood begins ...
Revised and expanded, the third edition of this respected manual offers the latest advice on preventing, evaluating, and managing diseases that can be acquired in tropical environments and foreign countries. New content includes information on lyme disease, HIV, infants and children, women, air travel, and more.
In Poverty and Neglected Tropical Diseases in the American Rural South, Christine Crudo Blackburn and Macey T. Lively study regions of the United States rarely acknowledged by the average American. These are regions of extreme poverty in the rural American South where a mixture of historical discrimination, structural discrimination, lack of opportunities, and decaying infrastructure conspire to create an environment conducive to chronic, debilitating diseases known as Neglected Tropical Diseases (NTDs). Blackburn and Lively explore the conditions that allow NTDs to thrive in a wealthy nation like the United States when such diseases are typically associated with the poorest communities in Africa, Asia, and South America. Poverty and Neglected Tropical Diseases pulls back the curtain on the reality of poverty and disease in America and tell the story of failing sanitation infrastructure, the lack of clean water, the inability to access healthcare, and the lack of financial security through the eyes of those living it every day.