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Innovations for Next-Generation Antibody-Drug Conjugates
Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (...
Directory of Pathology Training Programs
Describes training facilities, residencies, remuneration, application requirements, and faculty at approved programs for anatomic and clinical pathology in the U.S. and Canada. Also includes coverage of fellowships and postgraduate opportunities for training.
Antibody-Drug Conjugates and Immunotoxins
This volume gathers the leading research on antibody-drug conjugates and immunotoxins. Following a rigorous overview, the volume delves into focused sections on all aspects of ADCs and ITs from clinical development through to targeted therapeutic applications and the latest technologies.
The Happiness Prayer
At age 30 Evan Moffic became the leader of a large congregation. He had great success. But he couldn't find happiness. Then he found a 2000-year-old prayer. In it were hidden elements of Jewish wisdom. They became a part of his life and those of his congregation and transformed them and him. What if we had a clear path to follow when life disappointed us? What if we had a time-tested guide for a life of deeper meaning and happiness? That is what Rabbi Moffic discovered in an ancient Jewish prayer. Based on ten practices any person can follow, the prayer has helped thousands of people-couples, teenagers, empty nesters struggling with loss, divorce, and ruptured relationships-find renewed mean...
Balanced Constitutionalism
The Human Rights Act (HRA) of the UK, 1998, unlike systems of parliamentary sovereignty and judicial supremacy, promised a new, 'balanced' model for the protection of rights, which conferred courts with limited power of review over legislation. This book examines the promise of the new model against its performance in practice by comparing judicial review under the HRA to an exemplar of the old model of judicial review, the Indian Constitution.
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