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This book highlights modern techniques of research into Candida albicans, especially in terms of emerging and emerged pathogenic Candida species. It also looks at metabolic adaptation, resistance related to environmental stress and variety of nutrients, best performing plants that inhibit Candida's activities, interaction with other microbes, antifungal immunity mechanisms, and the posttherapeutic management of fungal infections. The book is a collection of very high impact research that includes a combination of biochemical, molecular biological, and medical microbiological innovative scientific techniques. It contains fascinating information that will help readers to explore and understand why C. albicans is different from other microbes. The authors describe this significant discovery using both bioinformatic and laboratory techniques and this uniqueness is the reason why C. albicans is a successful pathogenic yeast.
Some of the world's leading research scientists in the field have contributed to this new book on malaria vaccine development. The book examines various strategies being pursued against the different stages of the parasite (the sporozoite, asexual erythrocytic stages, and sexual stages). It describes vaccines that combat the parasite directly, vaccines aimed at preventing disease, vaccines based on attenuated parasites, and vaccines based on small, carefully defined synthetic peptides. The book provides a compendium of current approaches, lists of preferred antigens, and the results of vaccine trials to date. Molecular immunology involved with both the natural immune response to parasites and with the constraints on inducing immunity are emphasized throughout the book. Views on how vaccines may be tested and then integrated into malaria control programs are also discussed. Molecular Immunological Considerations in Malaria Vaccine Development will be useful for researchers and students in immunology, parasitology, biotechnology, vaccine design, and tropical and public health.
This book contains conference presentations regarding the regulation of eicosanoid enzymes and, in particular, cyclooxygenases, lipoxygenases, and phospholipases. The new field of isoprostanes is also represented.