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A comprehensive and authoritative text on the formation and evolution of planetary atmospheres, for graduate-level students and researchers.
Leading experts comprehensively review all aspects of the delivery of therapeutic molecules to cells using electrical impulses-i.e., the extraordinarily promising new areas of electrogenetherapy, electrochemotherapy, and transdermal drug delivery. Their survey ranges from outlines of the basic physical principles that govern cell permeabilization by pulsed electric fields, to descriptions of the current state-of-the-art in instrumentation and electrodes, to summaries of preclinical and clinical trial results. The authors focus on drug, gene, and transdermal delivery techniques, providing detailed examples of drug delivery using electric fields from a variety of pulse generators and electrodes. Comprehensive and authoritative, Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery: Electrically Mediated Delivery of Molecules to Cells provides entré to an immensely practical set of in vivo electroporation techniques, including electrogenetherapy, electrochemotherapy, and transdermal drug delivery-techniques holding great promise for all those working toward better therapies for cancer, metabolic diseases, and vaccination.
This edited collection offers the first systematic account in English of Italy’s international position from Caporetto – a major turning-point in Italy’s participation in the First World War – to the end of the liberal regime in Italy in 1922. It shows that after the ‘Great War’, not only did Italy establish itself as a regional power but also achieved its post-unification ambition to be recognised, at least from a formal viewpoint, as a great power. This subject is addressed through multiple perspectives, covering Italy’s relations and mutual perceptions vis-à-vis the Allies, the vanquished nations, and the ‘New Europe’. Fourteen contributions by leading historians reappraise Italy’s role in the construction of the post-war international order, drawing on extensive multi-archival and multi-national research, combining for the first time documents from American, Austrian, British, French, German, Italian, Russian and former Yugoslav archives.
IAU Transactions XXVIB contains the Proceedings of the IAU XXVII General Assembly held in Prague, 14-25 August 2006, hosting a total of 2412 participants from 73 countries. The Assembly featured a rich scientific program, comprising 6 Symposia, 17 Joint Discussions and 7 Special Sessions. During the program about 650 papers were presented and more than 1550 posters displayed. The Proceedings of the 6 Symposia have been published in the Proceedings of the IAU Symposia Series, and the proceedings of the Joint Discussions and Special Sessions feature in IAU Highlights of Astronomy, 14. Together with those 7 volumes, these Transactions cover the entire General Assembly. In addition to the scientific program, the XXVI General Assembly hosted the regular Business Meetings of the EC, the 12 Divisions, 40 Commissions and 75 Working Groups. This volume records the organizational and administrative business of the XXVI General Assembly and the status of the IAU membership.
Proceedings of the IAU Symposium No. 40, held in Marfa, Texas, U.S.A., October 26-31, 1969
Hello and welcome to Effective PyCharm. In this book, we're going to look at all the different features of one of the very best environments for interacting and creating Python code, PyCharm. PyCharm is an IDE (integrated development environment) and this book will teach you how you can make the most of this super powerful editor.The first thing we are going to talk about is why do we want to use an IDE in the first place? What value does a relatively heavyweight application like PyCharm bring and why would we want to use it? There are many features that make PyCharm valuable. However, let's begin by talking about the various types of editors we can use and what the trade-offs are there.We'r...
Over 800 million adults worldwide, two thirds of them women, are unable to reap the benefits of literate expression. In this book, the author aims to dispel the notion that illiteracy is principally confined to rural areas, which has for many years been the main focus of development programmes. Through a series of case studies and analysis this book provides a valuable insight into what literacy can mean in an urban setting and explores the many ways it is used to enhance the lives of individuals. It highlights the need for greater understanding of the diversity of literacy learning and explores the practical issues in providing assistance to those who aspire to improve their literacy skills.
Since comet Shoemaker-Levy collided with the planet Jupiter with stupendous force in 1994 there has been an upsurge of amateur interest in comets. Most comets are first discovered by amateur astronomers because there are so many amateurs looking for them, and techniques and instruments have improved dramatically in the past few years. After a short but detailed introduction to the comets themselves Nick James and Gerald North describe comet hunting, photographing and imaging comets, and digital image processing. The use of computers for orbital calculations and even helping to discover new comets is given a full chapter, as are advanced techniques including comet photometry and spectroscopy. This comprehensive book has an accompanying CD-ROM and is at once a "primer" for comet hunters and a reference text for more advanced amateur astronomers.
The conservation, sustainable use and development of aquatic genetic resources (AqGR) is critical to the future supply of fish. The State of the World’s Aquatic Genetic Resources for Food and Agriculture is the first ever global assessment of these resources, with the scope of this first Report being limited to cultured AqGR and their wild relatives, within national jurisdiction. The Report draws on 92 reports from FAO member countries and five specially commissioned thematic background studies. The reporting countries are responsible for 96 percent of global aquaculture production. The Report sets the context with a review of the state of world’s aquaculture and fisheries and includes o...
A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse including nicotine, alcohol and "designer" drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular toxicology. Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.