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This book gathers the papers of the PUDCAD Universal Design Practice Conference: Game + Design Education, organized by Istanbul Technical University and held online on June 24-26, 2020. The conference represented one of the key events of the Practicing Universal Design Principles in Design Education through a CAD-Based Game (PUDCAD) project, which developed a design game on a CAD-based platform, enabling students and designers to learn about universal design principles and develop accessible and innovative design ideas. As such, the PUDCAD project met one of the foremost goals of the European Commission, making sure the inclusion and efficient accessibility for people with disabilities into everyday life. The main topics of the conference include: universal design and education, universal design and user experience, game and design studies, gamification, virtual reality experiment, e-learning in design, and playful spaces and interfaces. The contributions, which were selected by means of a rigorous international peer-review process, highlight numerous exciting ideas that will spur novel research directions and foster multidisciplinary collaboration among different specialists.
Lasso peptides form a growing family of fascinating ribosomally-synthesized and post-translationally modified peptides produced by bacteria. They contain 15 to 24 residues and share a unique interlocked topology that involves an N-terminal 7 to 9-residue macrolactam ring where the C-terminal tail is threaded and irreversibly trapped. The ring results from the condensation of the N-terminal amino group with a side-chain carboxylate of a glutamate at position 8 or 9, or an aspartate at position 7, 8 or 9. The trapping of the tail involves bulky amino acids located in the tail below and above the ring and/or disulfide bridges connecting the ring and the tail. Lasso peptides are subdivided into ...
Dear Academicians, Readers and Educators, We are pleased to present the issue of the International Journal of Secondary Metabolite as a special issue entitled ‘I. International Congress on Medicinal and Aromatic Plants - “Natural And Healthy Life”’. This special issue contains some of scientific studies presented in the congress. Hosting the I. International Medical and Aromatic Plant Congress, held in Konya on 9-12 May 2017, by the coorperation T.R. Ministry of Forestry and Water Affairs, General Directorate of Forestry and Necmettin Erbakan University was a great honor for us. The total number of abstract submission for the congress was 1923. After the scientific evaluation, 85 abs...
International trade has grown rapidly over the past half century, accommodated by the transportation industry through concomitant growth and technological change. But while the connection between transport and trade flows is clear, the academic literature often looks at these two issues separately. This Handbook is unique in pulling together the key insights of each field while highlighting what we know about their intersection and ideas for future research in this relatively unexamined but growing area of study.
This book discusses key aspects of childhood acute lymphoblastic leukemia (ALL), presenting the latest research on the biology and treatment of the disease and related issues. The cure rate for ALL has improved dramatically due to advances such as supportive care, treatment stratification based on relapse risk, and the optimization of treatment regimens. Gathering contributions by eminent scholars Pediatric Acute Lymphoblastic Leukemia is a valuable resource for pediatric hematologists as well as for medical students, interns, residents and fellows. It not only offers comprehensive insights, but also provides a springboard for future research.
This book focuses on the global quality of the design of systems that people interact with during their work activities and daily lives; a quality that involves the globality of people’s experience – physical, sensory, cognitive and emotional. It presents a concise and structured overview of the ergonomic approach to planning, and of methodological and operational tools from ergonomic research that can more directly and concretely contribute to the design process. The book also explores physical ergonomics and cognitive ergonomics, which are essential components of design culture. The final section addresses the main design problems and intervention criteria regarding the design of envir...
The importance of emulsification techniques, their use in the production of nanoparticles for biomedical applications as well as application of rheological techniques for studying the interaction between the emulsion droplets is gathered in this reference work. Written by some of the top scientists within their respective fields, this book covers such topics as emulsions, nano-emulsions, nano-dispersions and novel techniques for their investigation. It also considers the fundamental approach in areas such as controlled release, drug delivery and various applications of nanotechnology.
Beginning with a general overview of nanocomposites, Bionanocomposites: Integrating Biological Processes for Bio-inspired Nanotechnologies details the systems available in nature (nucleic acids, proteins, carbohydrates, lipids) that can be integrated within suitable inorganic matrices for specific applications. Describing the relationship between architecture, hierarchy and function, this book aims at pointing out how bio-systems can be key components of nanocomposites. The text then reviews the design principles, structures, functions and applications of bionanocomposites. It also includes a section presenting related technical methods to help readers identify and understand the most widely used analytical tools such as mass spectrometry, calorimetry, and impedance spectroscopy, among others.
This volume contains five articles describing the mission and its instruments. The first paper, by the project scientist Richard C. Elphic and his colleagues, describes the mission objectives, the launch vehicle, spacecraft and the mission itself. This is followed by a description of LADEE’s Neutral Mass Spectrometer by Paul Mahaffy and company. This paper describes the investigation that directly targets the lunar exosphere, which can also be explored optically in the ultraviolet. In the following article Anthony Colaprete describes LADEE’s Ultraviolet and Visible Spectrometer that operated from 230 nm to 810 nm scanning the atmosphere just above the surface. Not only is there atmospher...