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The Mammalian Auditory Pathway: Neurophysiology
The Springer Handbook of Auditory Research presents a series of com prehensive and synthetic reviews of the fundamental topics in modern auditory research. It is aimed at all individuals with interests in hearing research including advanced graduate students, postdoctoral researchers, and clinical investigators. The volumes will introduce new investigators to important aspects of hearing science and will help established inves tigators to better understand the fundamental theories and data in fields of hearing that they may not normally follow closely. Each volume is intended to present a particular topic comprehensively, and each chapter will serve as a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in peer-reviewed journals. The series focusses on topics that have developed a solid data and con ceptual foundation rather than on those for which a literature is only beginning to develop. New research areas will be covered on a timely basis in the series as they begin to mature.
Pharmacology of 5-HT6 receptors, Part II
The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized, and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors. - Written by expert researchers - Covers all published literature to date in the field of 5-HT6 receptors
Recent Advances in the Use of Drosophila in Neurobiology and Neurodegeneration
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
The Oxford Handbook of Auditory Science: The Auditory Brain
Volume 1: The Ear (edited by Paul Fuchs) Volume 2: The Auditory Brain (edited by Alan Palmer and Adrian Rees) Volume 3: Hearing (edited by Chris Plack) Auditory science is one of the fastest growing areas of biomedical research. There are now around 10,000 researchers in auditory science, and ten times that number working in allied professions. This growth is attributable to several major developments: Research on the inner ear has shown that elaborate systems of mechanical, transduction and neural processes serve to improve sensitivity, sharpen frequency tuning, and modulate response of the ear to sound. Most recently, the molecular machinery underlying these phenomena has been explored and described in detail. The development, maintenance, and repair of the ear are also subjects of contemporary interest at the molecular level, as is the genetics of hearing disorders due to cochlear malfunctions.
Far From The Tree
**WINNER OF THE WELLCOME BOOK PRIZE 2014** A NEW YORK TIMES BESTSELLER Sometimes your child - the most familiar person of all - is radically different from you. The saying goes that the apple doesn't fall far from the tree. But what happens when it does? Drawing on interviews with over three hundred families, covering subjects including deafness, dwarfs, Down's Syndrome, Autism, Schizophrenia, disability, prodigies, children born of rape, children convicted of crime and transgender people, Andrew Solomon documents ordinary people making courageous choices. Difference is potentially isolating, but Far from the Tree celebrates repeated triumphs of human love and compassion to show that the shared experience of difference is what unites us. Winner of the National Book Critics Circle Award for General Non-fiction and eleven other national awards. Winner of the Green Carnation Prize.
Gaba in Autism and Related Disorders
Gamma-aminobutyric acid (GABA) was discovered in the brain in 1950 by Eugene Roberts. GABA is now considered one of the most important neurotransmitters and developmental signals. Knowledge on the complexity of GABA function is increasing exponentially. This volume covers basic research on GABA in the developing brain as it may relate to onset of autism and related developmental disorders. The evidence that dysfunction of GABA and related molecules is associated with autism is limited but expanding and seems to converge. Pertinent data are reviewed in this book and new research avenues in the basic and clinical arenas are described. The topics are of imminent interest to basic and clinical researchers as well as interested clinicians. * Discusses the neuropathology of the GABA system in autism * Presents new findings on common genetic mechanisms in Rett syndrome, Angelman syndrome, and autism * Includes information on the shared genetic risk factors between autism and major mental disorders * Foreword by Eugene Roberts
Basic Aspects of Hearing
The International Symposium on Hearing is a highly-prestigious, triennial event where world-class scientists present and discuss the most recent advances in the field of hearing research in animals and humans. Presented papers range from basic to applied research, and are of interest neuroscientists, otolaryngologists, psychologists, and artificial intelligence researchers. Basic Aspects of Hearing: Physiology and Perception includes the best papers from the 2012 International Symposium on Hearing. Over 50 chapters focus on the relationship between auditory physiology, psychoacoustics, and computational modeling.
The Auditory Cortex
Understanding human hearing is not only a scientific challenge but also a problem of growing social and political importance, given the steadily increasing numbers of people with hearing deficits or even deafness. This book is about the highest level of hearing in humans and other mammals. It brings together studies of both humans and animals thereby giving a more profound understanding of the concepts, approaches, techniques, and knowledge of the auditory cortex. All of the most up-to-date procedures of non-invasive imaging are employed in the research that is described.
The Neurobiology of Multiple Sclerosis
Multiple sclerosis (MS) is an immune-mediated neurodegenerative disorder of the human central nervous system (CNS) which usually affects young adults with certain genetic backgrounds who are then exposed to certain precipitating environmental antigen(s). Despite major advances of the past two decades in understanding the pathophysiology of MS, and in spite of the introduction of new immunomodulatory and immuno-suppressive agents which may slow down disease progression and delay the onset of disability, the "cause and the "cure for MS remain elusive. This volume of International Review of Neurobiology focuses on MS and related disorders. The volume can be divided into various sections with the main emphasis on MS pathogenesis, clinical features and epidemiology, neuroimaging, and treatment. The ultimate goal of this book is to encourage further research into the pathogenesis of this elusive disease.
Monoamine Oxidases and their Inhibitors
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. In this volume, invited experts provide authoritative reviews on various aspects of Monoamine Oxidase and its Inhibitors. - Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
