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DNA Repair and Cancer
DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topics include carcinogenesis as a predictive and/or prognostic biomarker for cancer therapy, nucleotide excision repair, and tumor genetics and personalized medicine. The contributions provide essential information to scientists, pharmaceutical investigators, and clinicians interested in cancer therapy.
Poultry Diseases
Now in its sixth edition, Poultry Diseases is once again fully revised with the addition of vital new material. It remains the standard reference work on health and disease for those involved in the poultry industry, government and veterinary education. Following a familiar structure, readers of the sixth edition gain concise but major reviews on current knowledge of general and disease-specific topics discussed over 45 (5 new) chapters in seven sections. With a large international team of contributors led by an authoritative editor team and a Foreword by Professor Frank Jordan, Poultry Diseases is an invaluable resource for the practicing veterinarian, poultry inspector, agricultural manage...
Myxozoan Evolution, Ecology and Development
This book provides an up-to-date review of the biology of myxozoans, which represent a divergent clade of endoparasitic cnidarians. Myxozoans are of fundamental interest in understanding how early diverging metazoans have adopted parasitic lifestyles, and are also of considerable economic and ecological concern as endoparasites of fish. Synthesizing recent research, the chapters explore issues such as myxozoan origins; evolutionary trends and diversification; development and life cycles; interactions with hosts; immunology; disease ecology; the impacts of climate change on disease; risk assessment; emerging diseases; and disease mitigation. This comprehensive work will appeal to a wide readership, from invertebrate zoologists, evolutionary biologists and developmental biologists to ecologists and parasitologists. It will also be of great practical interest to fisheries and conservation biologists. The identification of key areas for future research will appeal to scientists at all levels.
Molecular Diagnostics
The book takes the reader through definitions of the pharmacodiagnostic concept, historical perspectives of the early steps into molecular cancer diagnostics linked to therapy, ongoing research, assay validation, clinical trial methodology, regulatory issues around pharmacodiagnostics and future aspects within personalized cancer medicine.
Inside/outside
This analysis of how and why businesses buy outside legal services provides useful insights for businesses and law firms alike. In-house legal buyers at both Fortune 100 and new economy companies provide concrete examples of how some businesses have successfully and creatively restructured their in-house legal departments and their relationships with outside law firms. Included are many examples of firms that have successfully developed business and an examination of why other law firms fail at this important task. The subtle nuances that affect legal buying decisions and the impact of corporate globalisation, law firm mergers, and the advent of multidisciplinary practice groups are also explored.
