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Parkinson's disease becomes apparent only after substantial loss (>60%) of the dopamine neurons in the substantia nigra. By this time there has already been widespread neural inclusion formation in the peripheral and central nervous system of patients with the disease, although this has only been recognized more recently. Degeneration in these widespread regions of the peripheral and central nervous system is now known to impact on disease symptoms, progression and treatment over time. This book aims to provide a comprehensive review of these non-dopamine lesions in Parkinson's disease by assessing our current knowledge of their presence and pathophysiology, how they relate to different symp...
A comprehensive textbook of paediatric emergency medicine for trainee doctors - covers all the problems likely to present to a trainee in the emergency department. Short concise chapters, with key point boxes at the beginning - easy to use for the hard-pressed trainee. Aims to give a consensus approach to assessment and treatment, based on the latest evidence. Highlights areas of controversy.
A biting collection of stories from a bold new voice. A young girl sees ghosts from her third eye, located where her belly button should be. A corporate lawyer feels increasingly disconnected from his job in a soulless 1200-storey skyscraper. And a one-dimensional yellow man steps out from a cinema screen in the hope of leading a three-dimensional life, but everyone around him is fixated only on the color of his skin. Welcome to Portable Curiosities. In these dark and often fantastical stories, Julie Koh combines absurd humour with searing critiques on modern society, proving herself to be one of Australia's most original and daring young writers.
An overview of the latest interdisciplinary research on human morality, capturing moral sensibility as a sophisticated integration of cognitive, emotional, and motivational mechanisms. Over the past decade, an explosion of empirical research in a variety of fields has allowed us to understand human moral sensibility as a sophisticated integration of cognitive, emotional, and motivational mechanisms shaped through evolution, development, and culture. Evolutionary biologists have shown that moral cognition evolved to aid cooperation; developmental psychologists have demonstrated that the elements that underpin morality are in place much earlier than we thought; and social neuroscientists have ...
The updated third edition of Cognitive Assessment for Clinicians is a theoretically-motivated guide to the assessment of patients with cognitive complaints.
Increasing interest over recent years in the study of the influences of environment and genetic factors on behavioural disorder has come from a wide range of disciplines. These studies have subsequently been focused through the foundation of the Society for the Study of Behavioural Phenotypes, which forms the basis for assimilating new information and coordinating future research in this field. This volume from founder members of the society presents a distillation of thinking and reviews appropriate measurement schedules. Including research findings, explanation of concepts, genetic scientific techniques and methodological issues, this work will be welcomed by those with an interest in behavioural disorder at every level.
Includes information on: basic training requirements; the written examination; an approach to the clinical examination; the long case, the short case and examples. Talley, University of Sydney; O'Connor, Canberra Hospital, Australia.
Examines molecular biologic techniques including proteomics, genomics, targeted therapies, RNA interference, cDNA arrays, and tissue arrays. This book contains sections discussing bioinformatics and societal issues in oncology, including regulatory issues, telemedicine, and international differences in oncology.