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Parkinson's disease becomes apparent only after substantial loss (>60%) of the dopamine neurons in the substantia nigra. By this time there has already been widespread neural inclusion formation in the peripheral and central nervous system of patients with the disease, although this has only been recognized more recently. Degeneration in these widespread regions of the peripheral and central nervous system is now known to impact on disease symptoms, progression and treatment over time. This book aims to provide a comprehensive review of these non-dopamine lesions in Parkinson's disease by assessing our current knowledge of their presence and pathophysiology, how they relate to different symp...
Movement Disorders 4, the newest volume in the Blue Books in Neurology series provides you with rapid access to practical, clinical guidance on the diagnosis and pharmacologic treatment on the full range of movement disorders. Emphasizes the vast array of pharmacologic therapeutics, backed by clinical trials of the past 15 years to help you determine the best and most up-to-date drug therapy. Provides the latest on hot topics such as frontotemporal dementia and Tourette’s and related disorders, keeping you up to date on today’s issues. Presents the surgical management of Parkinson’s Disease to help you determine when to recommend surgery and for which patients. Includes extensive comprehensive information on Parkinson’s so you can better diagnose and treat PD patients. Offers more clinical details on tremors, differentiating between PD and other movement disorders and the genetics of movement disorders so you can determine which movement disorder is present.
Winner of the BMA 2011 book awards: psychiatry category Winner of the Australian Journal of Ageing book of the year award This definitive work on dementia and related disorders has been fully updated and revised to reflect recent advances in this fast-moving field. The incidence of dementia continues to rise as the population of the world ages, and the condition represents one of the most significant challenges facing societies and health professionals in the next half-century. In this, the most comprehensive single volume work available on the subject, the editors have met this challenge by assembling a team of the world's leading experts on all aspects of the condition, from history, epidemiology and social aspects to the latest neurobiological research and advanced therapeutic strategies.
A directory to the universities of the Commonwealth and the handbook of their association.
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Filling a noticeable gap in the market for a new text solely focused on Dementia with Lewy Bodies, this book discusses cutting-edge topics covering the condition from diagnosis to management, as well as what is known about the neurobiological changes involved. With huge progress having been made over the last decade in terms of the disorder
This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.
Atlas of the Developing Mouse Brain, Second Edition builds on the features of successful first edition, providing a comprehensive and convenient reference for all areas of the mouse brain at Fetal-Day 17.5 (E17.5), Day-of-Birth (P0), and Day-Six postnatal (P6). The book also delineates the parts of the eye, features of the skull, ganglia, nerves, arteries, veins, bones and foramina. This atlas is an essential tool for researchers and students who study the development of the mouse brain, or for those who interpret findings from genetic manipulation. - Contains 176 high-resolution color scans of Nissl-stained coronal sections of the brain and skull of the fetal (E17.5), day-of-birth (P0), and day-six postnatal mouse (P6) - Includes diagrams that delineate all structures of the brain, as well as peripheral nerves, ganglia, muscles, bones, veins and arteries of the head - Presents approximately 5000 corrections and updates from the first edition - Includes color codes of the veins, arteries, nerves and ganglions of the skull in diagrams