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This book provides a comprehensive account of the pathogenesis and treatment of intestinal fibrosis, covering both the clinical and molecular aspects of the disease. It begins by describing the epidemiology and genetics of fibrostenosing IBD in Crohn’s disease and Ulcerative colitis as well as the epigenetics and cellular and molecular mechanisms of the disease. Readers will obtain an in-depth overview of the disease from biomarkers and histology to surgical intervention, imaging and current and future drug therapies. Medical management of fibrosis, endoscopy and imaging as well as surgical approaches are all discussed. Through the links to videos contained in the book, the reader will become familiar with interventional procedures such as endoscopic balloon dilation and surgical techniques for stricturing IBD, such as resection and strictureplasties. This is an indispensable volume for anyone working on fibrostenotic IBD, such as gastroenterologists, internists, radiologists, colorectal surgeons, pathologists and researchers. It has been written by a team of top experts from North America, Asia and Europe.
Do you suffer from painful abscesses in the armpits, groin or genital area? Have you ever heard of "Acne Inversa" (Hidradenitis suppurativa) or do you suspect you suffer from the little researched disease? Do you want to know everything about "Acne Inversa" and how to deal with the disease? The guide offers you comprehensive information about "Acne Inversa". The chronic disease attacks your body. It is considered a systemic disease. You will learn what you are dealing with in the disease "Acne Inversa". Look forward to honest information and tried and tested tips from the author, which have already proven themselves in practice. You will receive detailed descriptions of the various therapeut...
In diesem Buch stellen führende Internisten und Chirurgen die Therapie chronisch entzündlichen Darmerkrankungen wie Morbus Crohn und Colitis ulcerosa umfassend und handlungsorientiert dar. Sie beschreiben die jeweils spezifischen Aspekte der Behandlung, aber insbesondere auch die Schnittstellen der interdisziplinären Zusammenarbeit, die eine enge Abstimmung zwischen Internisten und Chirurgen erfordert. Die primäre, medikamentöse Therapie wird dem operativen, möglichst darmerhaltenden Vorgehen gegenüber gestellt. Diagnostik, Sondersituationen (z.B. Pouchitis), extraintestinalen Manifestationen und therapieassoziierten Komplikationen sind eigene Kapitel gewidmet. Abgerundet wird das Buch durch Pathogenese und Epidemiologie, Besonderheiten der CED in unterschiedlichen Lebensabschnitten sowie Begleittherapien.
As the number of patients with colitis-associated cancer (CAC) is on the increase, the purpose of this book is to review the latest topics concerning management of the disease. In recent years, the diagnostic power of endoscopy and molecular pathology has also grown tremendously, as a result of which they now have a far greater influence on the treatment of CAC. At the moment, appropriate monitoring programs for ulcerative colitis and Crohn’s disease remain uncertain. At the same time, the latest findings on DNA methylation and microRNAs hold the promise of making revolutionary changes in these areas. Moreover, recent drug advances in the treatment of inflammatory bowel diseases have changed surgical indications. On the other hand, the indication of mucosectomy on colorectal cancer in ulcerative colitis and prophylactic abdominoperineal resection for Crohn’s disease remain controversial. This book provides the latest information on the remaining issues of CAC from the point of view of expert surgeons.
Inflammatory bowel diseases are increasingly common and complex. Modern therapeutic strategies involve infusion therapy and the use anti-TNF or other biologicals as well as intravenous iron preparations. This book covers the pathophysiology and treatment of anemia in inflammatory bowel diseases and discusses controversial aspects specifically when it comes to iron therapy.
An easily accessible guide to diagnosing and managing critical situations, Emergencies in Gastroenterology and Hepatology aids doctors in dealing with acutely sick patients quickly and effectively. The book provides practical advice on how to make difficult decisions in an emergency situation. Areas covered include life and death emergencies, as well as the broad problems faced by on-call Gastroenterologists and Hepatologists on a daily basis. The focus throughout is on immediate management, but the book also includes reference to long term follow up for certain problems. Each chapter has an associated algorithm, which summarises the contents of the chapter, providing an aide memoir for the reader and facilitating learning, as well as being a quick reference tool. Bullet-point information for speed and clarity combined with the integral cross-referencing system, further enables quick access to the necessary information.
This volume provides the first full-scale commentary on the eighth book of Virgil’s Aeneid, the book in which the poet presents the unforgettable tour of the site of the future Rome that the Arcadian Evander provides for his Trojan guest Aeneas, as well as the glorious apparition and bestowal of the mystical, magical shield of Vulcan on which the great events of the future Roman history are presented – culminating in the Battle of Actium and the victory of Octavian over the forces of Antony and Cleopatra. A critical text based on a fresh examination of the manuscript tradition is accompanied by a prose translation.