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Now in its third edition and supplemented with more online material, this book aims to make the "new" information-based (rather than gene-based) bioinformatics intelligible both to the "bio" people and the "info" people. Books on bioinformatics have traditionally served gene-hunters, and biologists who wish to construct family trees showing tidy lines of descent. While dealing extensively with the exciting topics of gene discovery and database-searching, such books have hardly considered genomes as information channels through which multiple forms and levels of information have passed through the generations. This “new bioinformatics” contrasts with the "old" gene-based bioinformatics that so preoccupies previous texts. Forms of information that we are familiar with (mental, textual) are related to forms with which we are less familiar (hereditary). The book extends a line of evolutionary thought that leads from the nineteenth century (Darwin, Butler, Romanes, Bateson), through the twentieth (Goldschmidt, White), and into the twenty first (the final works of the late Stephen Jay Gould). Long an area of controversy, diverging views may now be reconciled.
Major inconsistencies in Darwin's theory of the origin of species by natural selection remained unresolved for over a century until the results of recent research in various genome projects led to the theory's reinterpretation. Reviewing this new information, Donald Forsdyke, a laboratory scientist involved in genome research, wondered whether similar discoveries could have been made a century earlier, by one of Darwin's contemporaries. The Origin of Species Revisited describes his investigation into the history of evolutionary biology and its startling conclusion. The trail led first to Joseph Hooker and Thomas Huxley, who had been both the theory's strongest supporters and its most penetra...
This biography provides an understanding of William Bateson as well as a reconciliation of diverging views (e.g. the hierarchical thinking of Gould and the genocentrism of George Williams and Richard Dawkins). Evolutionists may thus, at long last, present a unified front to their creationist opponents. The pressing need for this text is apparent from the high percentages reported not to believe in evolution and the growth of the so-called "intelligent design" movement.
This biography provides an understanding of William Bateson as well as a reconciliation of diverging views (e.g. the hierarchical thinking of Gould and the genocentrism of George Williams and Richard Dawkins). Evolutionists may thus, at long last, present a unified front to their creationist opponents. The pressing need for this text is apparent from the high percentages reported not to believe in evolution and the growth of the so-called "intelligent design" movement.
Jacket.
Books on bioinformatics which began appearing in the mid 80s primarily served gene-hunters, and biologists who wished to construct family trees showing tidy lines of descent. Given the great pharmaceutical industry interest in genes, this trend has continued in most subsequent texts. These deal extensively with the exciting topic of gene discovery and searching databases, but hardly consider genomes as information channels through which multiple forms and levels of information, including genic information, have passed through the generations.
Discussing the laws in the current research funding decision process, the author suggests ways to improve future funding of health research systems. Chapters recount ways of raising funds, the tragic way authorities improperly introduced diptheria immunization, consideration of how the peer review system evolved in response to massive infusion of funds in the nineteen forties, and the status quo generating a climate conducive to ethics violations, among others. This fascinating work will be an invaluable tool to researchers, health care workers, members of government agencies and those in charitable organizations that support health research, as well as to anyone interested in current trends in this area, including patients.
Most studies of ancient Greek politics focus on formal institutions such as the political assembly and the law courts, and overlook the role that informal social practices played in the regulation of the political order. Sara Forsdyke argues, by contrast, that various forms of popular culture in ancient Greece--including festival revelry, oral storytelling, and popular forms of justice--were a vital medium for political expression and played an important role in the negotiation of relations between elites and masses, as well as masters and slaves, in the Greek city-states. Although these forms of social life are only poorly attested in the sources, Forsdyke suggests that Greek literature rev...
This book explores the essence of immunity. After an initial review of hypotheses, models, and theories proposed to explain immune phenomena in humans and mice, it summarizes the results from synchronic organism‐level analyses and diachronic analyses tracing phylogeny. These results suggest that immunity is coextensive with life and is equipped with functions similar to the nervous system. Philosophical reflection with reference to Spinoza and Canguilhem suggests immunity is part of the essence of life—and the essence of immunity embraces mental elements with normativity. Approaching the essence of any phenomenon in this way is called "metaphysicalization of science." This book demonstrates the potential of this approach and contributes to a richer understanding of nature. Key Features Reviews the history of immunological theories Discusses and integrates science and philosophy Provides a biological framework for cognition and self vs. nonself Inspired by Auguste Comte’s "The Law of Three Stages"