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Immunology has become one of the most important of the life sciences. As research unravels the mystery of the lymphocyte, a central role of the immune system in health preservation has become evident. The paediatric immunodeficiency disorders or 'experiments of nature' have demonstrated the division of cellular and humoral immunity; specific functional defects are now readily identified. The tendency of persons with immune dysfunction to develop neoplasms has suggested that surveillance mechanisms within the immune apparatus prevent tumour development. Malignancies, in fact, do seem to provoke certain immune responses, begging numerous therapeutic questions. Transplantation surgery, or the d...
Recent developments have favourably and extensively altered general surgical practice. As editor I have happily been able to select certain topics of new and major interest for detailed discussion and have thus had the opportunity to collect these authoritative submissions within the covers of one text. The range of topics is broad. Endoscopy has changed the nature of both investigation and treatment of much gastrointestinal disease and the therapeutic uses of endoscopy continue to grow. That sophisticated new tool of the radiologist, computerized axial tomography, has revolu tionized the diagnosis of intra-abdominal disease, very often permitting precise localization of hitherto occult dise...
On May 14-16, 1982, a group of scientists met in Viareggio, Italy to present ideas, and exchange relevant data on current approaches on immunomodulators. We felt that the embodiment of the substance of that international symposium into this volume will be beneficial in keeping both clinicians and basic scientists abreast of the latest exciting developments in this rapidly accelerating field. We hope that the publication of this series of papers by an international panel of experts will enhance the nature of future inves t igat ive stud ies with such ent it ies . Under the rubric of immunology, it is obvious that such a term as "immunomodulation" could be construed as being all encompassing. ...
This book details all aspects of lung transplantation and equips the general pulmonologist/physician with the necessary tools and knowledge to assist patients with the preparation for and care post lung transplantation. Written by global experts, chapters present general principles and history; indications and eligibility for lung transplantation, including screening for COPD, cystic fibrosis, scleroderma, Idiopathic pulmonary fibrosis (IPF) and idiopathic pulmonary arterial hypertension; approach to and complications of lung transplantation, such as prognostic markers, radiological approach, and immunology and rejection; and medical and surgical guidelines for lung transplantation. The goal...
R. Y.Calne Surgeons are transplanting kidneys in ever increasing numbers-more than 10000 renal allografts have now been reported to the Transplant Registry. With related donors 75% of grafted kidneys continued to function after 2 years, compared with 50% when the donors were unrelated. The therapeutic value is obvious, but the management is largely empirical and results have improved little in the past 5 years. The basic sciences related to tissue transplantation have advanced rapidly. New serological and tissue culture techniques and chemical analysis of antigens and anti bodies have produced complicated data that is almost incomprehensible to the non specialist. Mathematical treatment of g...
First multi-year cumulation covers six years: 1965-70.
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Immunobiology of Transfer Factor compiles research papers presented at the Fourth International Transfer Factor Workshop, held at the Given Institute of Pathobiology in Aspen, Colorado, on October 3-6, 1982. This book focuses on the immunologic effects of transfer factor, which are supported by in vitro and in vivo experiments that indicate immunologically specific interactions between transfer factor and antigens. The topics include the selective removal of transfer factor activity with antigen, antigen-specific suppressor factor in human leukocyte dialysates, and specific suppressor dialysates from mice. The kinetics of immune response and production of transfer factor in bovine, dialyzable leukocyte extracts in pulmonary diseases, and mechanisms of action of human transfer factor are also elaborated. This compilation is suitable for microbiologists, immunologists, and specialists researching on transfer factor.