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The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance
The focus of this eBook is to bring new insights into central immune tolerance. To fulfill that, much has been discussed about the master in the regulation of tolerance, the autoimmune regulator (Aire) gene the main thymus cell type that expresses this gene, the medullary thymic epithelial cells (mTECs). It includes one Editorial and 12 other excellent contributions in the format of mini reviews or original research papers covering one or more of these aspects: promiscuous gene expression (PGE), epigenetics, miRNAs, association of the Aire gene and miRNAs, thymocyte–TEC interaction, coxsackievirus and type 1 diabetes, exosomes in the thymus, thymic crosstalk, thymic B cells, T cell develop...
Highlights of Spanish Astrophysics IV
This volume documents the contributions presented at the Seventh Scientific Meeting of the Spanish Astronomical Society (Sociedad Española de Astronomía, SEA). The event bought together 301 participants who presented 161 contributed talks and 120 posters, the greatest numbers up to now. The fact that most exciting items of the current astronomical research were addressed in the meeting proofs the good health of the SEA, a consolidated organization founded fifteen years ago in Barcelona. Two plenary sessions of the meeting were devoted to the approved entrance of Spain as a full member of the European Southern Observatory (ESO) and to the imminent first light of the greatest telescope in the world, the GTC (Gran Telescopio de Canarias), milestones that will certainly lead the Spanish Astronomy in the next future.
Transactions of the International Astronomical Union
The XXth General Assembly of the International Astronomical Union was held in Baltimore, Maryland USA from August 02 to 11, 1988. The Inaugural Ceremony on August 02 was held in the presence of representatives of the United States Governn:ent, t~e S~ate of Maryland, the City of Baltimore and the host institution -the Johns Hopkins Umverslty- as well as of the National and Local Organising Committees. The scientific programme maintained the high standards of the Union and the scientific proceedings may be found either in this volume or in volume 8 of Highlights of Astronomy. The scientific programme was organised by the 40 Commission Presidents and coordinated by the General Secretary (1985-1988), Dr. J.-P. Swings. The local arrangements were effectively made through the National Organising Committee under the Chairmanship of Prof. F. Drake and the Local Organising Committee under the co-Chairmanship of Prof. A. Oavidsen and Dr. R. Giacconi. The smooth day to day operation of the meeting resulted from the incomparable dedication of Karen Weinstock and Harold Screen.
Highlights of Spanish Astrophysics III
This volume contains the Proceedings of the Fifth Scientific Meeting of the Spanish Astronomical Society (Sociedad Espanola de Astronomfa, SEA). The meeting was held at the Universidad de Castilla La Mancha in Toledo, from September 9 to 13, 2002. The event brought together 219 participants who pre sented their latest results in many different subjects. In comparison with the previous scientific meetings of the Society, the numbers of oral talks and poster contributions (122 and 64, respectively) are rapidly increasing, confirming that the SEA conferences are becoming a point of reference to assess the interests and achievements of astrophysical research in Spain. During the meeting, the SEA...
Asteroseismology Across the HR Diagram
This book aims to facilitate a cross-fertilisation of ideas and approaches between fields covering different pulsators and with different areas of expertise. The book successfully covers most known types of pulsators, reflecting a highly productive and far reaching interchange of ideas which we believe is conveyed by the papers and posters published, making it a reference for researchers and postgraduate students working on stellar structure and evolution.
Circulation Weather types as a tool in atmospheric, climate and environmental research
Classifications of circulation weather systems have a long history in meteorology and climatology. Starting with manual classifications over specific regions of the globe, these tools (generally called “catalogs of synoptic types”) were restricted mainly to weather forecasting and historical climate variability studies. In the last decades, the advance of computing resources and the availability of datasets have fostered the development of fast and objective methods that process large amount of data. In recent years numerous methods of circulation type classification have been designed, showing their usefulness on a wide range of applications in scientific domains related to weather, climate, and environment. This Research Topic highlights methodological advances in circulation weather types and also their applications to different research areas. The articles included in this research topic show that circulation weather types can be used not only in Europe, where they have been always more frequent, but also applied to other regions of the world.
Cosmic Ray Diffusion in the Galaxy and Diffuse Gamma Emission
The original work presented in this thesis constitutes an important contribution to modern Cosmic Ray (CR) physics, and comes during one of the most exciting periods of this field. The first part introduces a new numerical code (DRAGON) to model the CR propagation in our Galaxy. The code is then used to perform a combined analysis of CR data, making it possible to determine their propagation properties with unprecedented accuracy. The second part is dedicated to a theoretical interpretation of the recent crucial experimental results on cosmic electron and positron spectra (PAMELA, Fermi-LAT experiments). Using the tools developed in the first part of the thesis, the author convincingly argues for the existence of a new spectral component, which could arise either from local astrophysical sources, such as pulsars, or from Dark Matter annihilation or decay. This thesis is a highly advanced work; the methods, analysis and results are clearly and carefully presented. This work is set to become an important reference document for any future work in this area.
