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Human Cancer Viruses
The first identification of a tumor-causing virus, Rous sarcoma virus, occurred almost 100 years ago, but it was not until the 1970s that the genetic basis for oncogenesis by this and other acutely transforming retroviruses was appreciated. Since then, numerous viral oncogenes and their corresponding cellular proto-oncogene counterparts have been identified, and these studies have contributed much to our understanding of crucially important aspects of cell biology and transformation.This book provides an up-to-date overview of the 6 major viruses that cause human cancers - HPV, HBV, HCV, EBV, KSHV and HTLV-1 - with respect to their molecular biology and epidemiology and to clinical aspects of disease, therapy and prevention. Contributed by over a dozen internationally renowned scientists, the chapters are comprehensively written and illustrated. The book is suitable for advanced students, postdoctoral researchers, scientists and clinicians who wish to understand the mechanisms leading to cellular transformation and oncogenesis by these viruses as a basis for the development of specific therapeutic and antiviral treatments.
Russian Postmodernism
The last ten years were decisive for Russia, not only in the political sphere, but also culturally as this period saw the rise and crystallization of Russian postmodernism. The essays, manifestos, and articles gathered here investigate various manifestations of this crucial cultural trend. Exploring Russian fiction, poetry, art, and spirituality, they provide a point of departure and a valuable guide to an area of contemporary literary-cultural studies which is currently insufficiently represented in English-language scholarship. A brief but useful "Who's Who in Russian Postmodernism" as an appendix introduces many authors who have never before appeared in a reference work of this kind and renders this book essential reading for those interested in the latest trends in Russian intellectual life.
Viral Infections and Treatment
Examining the pathology and transmission of the most common viral diseases, this reference compiles reviews by international specialists which detail breakthroughs in patient management, diagnostics and treatment of viral infections. The text also describes specific therapeutic agents according to their mode of action and clinical applications, as
Jean Epstein
Filmmaker and theoretician Jean Epstein profoundly influenced film practice, criticism and reception in France during the 1920s and well beyond. His work not only forms the crux of the debates of his time, but also remains key to understanding later developments in film practice and theory. Epstein's film criticism is among the most wide-ranging, provocative and poetic writing about cinema and his often breathtaking films offer insights into cinema and the experience of modernity. This collection - the first comprehensive study in English of Epstein's far-reaching influence - arrives as several of the concerns most central to Epstein's work are being reexamined, including theories of perception, realism, and the relationship between cinema and other arts. The volume also includes new translations from every major theoretical work Epstein published, presenting the widest possible historical and contextual range of Epstein's work, from his beginnings as a biology student and literary critic to his late film projects and posthumously published writings.
Spouted and Spout-Fluid Beds
Since the pioneering text by Mathur and Epstein over 35 years ago, much of the work on this subject has been extended or superseded, producing an enormous body of scattered literature. This edited volume unifies the subject, pulling material together and underpinning it with fundamental theory to produce the only complete, up-to-date reference on all major areas of spouted bed research and practice. With contributions from internationally renowned research groups, this book guides the reader through new developments, insights and models. The hydrodynamic and reactor models of spouted and spout-fluid beds are examined, as well as such topics as particle segregation, heat and mass transfer, mixing and scale-up. Later chapters focus on drying, particle-coating and energy-related applications based on spouted and spout-fluid beds. This is a valuable resource for chemical and mechanical engineers in research and industry.
Mechanisms of DNA Tumor Virus Transformation
Approximately 15% of human cancer incidence can be attributed to virus infection, i.e. viruses represent the second most important risk factor (after tobacco consumption) for cancer development in humans. Today, five virus types are known to be involved in causing human cancer: papillomaviruses, retroviruses, herpesviruses, hepadnaviruses, and flaviviruses. This volume of ‘Monographs in Virology’ provides a comprehensive review of a number of DNA tumor viruses. Leading experts in the field of tumor virology discuss up-to-date information, focusing on the transforming genes of DNA tumor viruses, the mechanisms of transformation and the in vitro methodology used for their identification an...
Viral Infections of Humans
Striking changes have occurred in the world since the publication of the last edition of Viral Infections of Humans. The global population is rapidly approaching 8 billion; climate change is leading to the introduction of new hosts, vectors and virus diseases heretofore never seen in many parts of the world; technological advances have revolutionized the ability to recognize and characterize viruses new and old; vaccines are altering the epidemiological landscape of the diseases they target, in some cases raising the hope of their eradication and remarkably powerful computational tools are enabling not only detection of outbreaks of disease much sooner than in the past but also, through comp...
Studies in Jewish Babylonian Aramaic
This book is the first wide-ranging study of the grammar of the Babylonian Aramaic used in the Talmud and post-Talmudic Babylonian literature (henceforth: Rabbinic Babylonian Aramaic) to be published in English in a century. The book takes as its starting point the long-recognized problem of the corrupt nature of the later textual witnesses of Babylonian Rabbinic literature and seeks both to establish criteria for the identification of accurate textual witnesses and describe the grammar of Rabbinic Babylonian Aramaic. The book is both programmatic and descriptive: it lays the foundations for future research into the dialect while clarifying numerous points of grammar, many of which have not ...
Handbook of Family Therapy
Integrative, research-based, multisystemic: these words reflect not only the state of family therapy, but the nature of this comprehensive handbook as well. The contributors, all well-recognized names who have contributed extensively to the field, accept and embrace the tensions that emerge when integrating theoretical perspectives and science in clinical settings to document the current evolution of couples and family therapy, practice, and research. Each individual chapter contribution is organized around a central theme: that the integration of theory, clinical wisdom, and practical and meaningful research produce the best understanding of couple and family relationships, and the best tre...
Viruses and Human Cancer
Viruses and Human Cancer provides a comprehensive review of the seven currently known human tumor viruses and their associated cancers with an emphasis on epidemiology, clinicopathologic features, and pathogenesis. Chapters are written by internationally recognized experts and all are generously illustrated with tables, diagrams and photographic images. Viruses and Human Cancer is designed to serve as a concise review of the field of human tumor virology for pathologists, oncologists and infectious disease specialists. It will also be of great value to practicing physicians, residents and clinical fellows in these specialties.
