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"As conceived, this history was aimed at satisfying the need of employees of the Central Intelligence Agency, especially new or young professional ones, for a comprehensive and detailed account of the agency's origin. It was completed in 1975, classified SECRET, and reproduced in sets of 2 volumes each. The security classification has recently been reviewed, and the manuscript, shorn of no more than six typewritten pages of material, is now declassified. Thus released for leisurely reading outside the office, and printed in one volume, this history should better serve its original purpose."--Preface.
Includes maps of the U.S. Congressional districts.
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Introduction to Biological and Small Molecule Drug Research and Development provides, for the first time, an introduction to the science behind successful pharmaceutical research and development programs. The book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the business and management issues of these approaches. The latter part of the book provides carefully selected real-life case studies illustrating how the theory presented in the first part of the book is actually put into practice. Studies include Herceptin/T-DM1, erythropoietin (Epogen/Eprex/NeoRecormon), anti-HIV protease in...