Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Match Race Mayhem
Drag racing is a very regulated sport. In the history of the NHRA, IHRA, and other sanctioning bodies, many classes existed in an effort to make sure the cars racing against each other are as equal as possible. It is a noble, if not futile, pursuit. You have two cars facing off that have very similar statistics in terms of weight, transmission type, fuel type, estimated horsepower, and all other sorts of measurables. The byproduct is that often the races that were "fair" were not the races that the fans wanted to see. During the golden age of drag racing, fans didn't care as much about class racing as much as they wanted to see scores settled, rivalries battled, and interesting match-ups. Th...
Novel Biomarkers for Predicting Response to Cancer Immunotherapy
Immunotherapy has revolutionized the treatment of malignancies. Targeting of immune checkpoints cytotoxic T-lymphocyte-associated protein 4, programmed cell death protein 1 (PD-1) and its ligand (PD-L1) has led to improving survival in a subset of patients. Despite their remarkable success, clinical benefit remains limited to only a subset of patients. A significant limitation behind these current treatment modalities is an irregularity in clinical response, which is especially pronounced among checkpoint inhibition. Currently, relevant predictors of cancer immunotherapy response include microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR), expression of PD-L1, tumor mutati...
Ribozymes and siRNA protocols
In this completely updated and expanded edition of a classic bench manual, hands-on experts take advantage of the latest advances in ribozyme, DNAzyme, hammerhead ribozymes and derivatives, and RNA interference technologies to describe in detail the exciting and successful methods now available for gene inactivation in vitro and in vivo. Their optimized techniques employ hairpin ribozymes, DNAzymes, hammerhead ribozymes and derivatives, group I intron ribozymes, RNase P ribozymes, and siRNAs, as well as general methods for RNA structure analysis, delivery of oligonucleotides, and gene therapy. Also provided are novel methods for identifying accessible cellular mRNA sites; group I intron and ...
Flyfisher's Guide to Mexico
Mexico has enough flyfishing opportunities to keep an angler busy for decades, and author Phil Shook breaks it down from Baja to the Yucatan and well beyond. Everything from tourist destinations like Cancun, Mazatlan and Acapulco, to lesser known locales such as Campeche, Ascension Bay, Tampico, Veracruz, Xcalak and much more, Shook has dedicated years of his life to researching Mexico's vast fisheries, and readers are privy to his insights in this all-inclusive book. If it's a viable sport-fishery, it's in the book. Shook guides anglers to the best tarpon, permit, bonefish and roosterfish fishing, while giving tips to steer them clear from potential trouble. Shook also details the best lodg...
Critical Monks
In Critical Monks Wallnig offers a new, contextualized interpretation of German Benedictine scholarship around 1700.
Notizie Del Giorno
None
Latent Variable Models and Factor Analysis
Latent Variable Models and Factor Analysis provides a comprehensive and unified approach to factor analysis and latent variable modeling from a statistical perspective. This book presents a general framework to enable the derivation of the commonly used models, along with updated numerical examples. Nature and interpretation of a latent variable is also introduced along with related techniques for investigating dependency. This book: Provides a unified approach showing how such apparently diverse methods as Latent Class Analysis and Factor Analysis are actually members of the same family. Presents new material on ordered manifest variables, MCMC methods, non-linear models as well as a new ch...
Antiangiogenic Agents in Cancer Therapy
Beverly Teicher and a panel of distinguished investigators survey the state-of-the-art of antiangiogenesis research from the lab bench to clinical trials. Timely and authoritative, the contributors summarize our current understanding of tumor growth and its dependence on vascular development, as well as the present status of antiangiogenic agents in preclinical and clinical development. In addition, the book also examines what is known about the mechanisms by which these therapeutic agents interfere with tumor vasculature and grapples with the problem of establishing criteria by which to assess their clinical efficacy. Antiangiogenic Agents in Cancer Therapy offers a unique cutting-edge compendium of antiangiogenic research, taking stock of what has been accomplished , where the experimental therapeutics of antiangiogenic agents is going, and the continuing evolution of their role in cancer treatment and novel drug development.
