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This new book covers drinking water regulations such as disinfectant by-products, synthetic organics, inorganic chemicals, microbiological contaminants, volatile organic chemicals, radionuclides, fluoride, toxicological approaches to setting new national drinking water regulations, and trihalomethanes. In addition, organic and inorganic compounds scheduled to be regulated in 1989 and new candidates for the 1990s regulations are detailed.
A comprehensive review and evaluation of the public health benefits and risks of fluoride in drinking water and other sources. Covers: properties, metabolism and sources of fluoride; health benefit assessment of fluoride; health risk assessment of fluoride; findings and conclusions; and recommendations. Extensive bibliography. Includes 8 appendices: surveys of dental fluoride prevalence, 1939-1987; osteosarcoma; gentoxicity of fluoride, and much more.
Toxicokinetics in Risk Assessment discusses the noncancer risk assessment process and its reliance on uncertainty factors in order to facilitate the continued study and refinement of the scientific basis for health risk assessment. This text clearly demonstrates the application of physiologically-based pharmacokinetic (PBPK) modeling in human healt
Toxicology is an integral part of the risk assessment process. In this book, investigators from the scientific and regulatory communities describe recent technical developments in risk assessment embracing toxicology and its allied sciences, risk qualification and characterisation, risk management, and risk communication. Case studies pertaining to current issues involving chemical and environmental risks, including military and industrial scenarios, are presented. Chapters describe value and ethical choices underlying toxicological decisions, economic and legal implications of regulations, understanding risk, and recommendations of the commission on risk assessment and risk management.