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The only comprehensive overview of the molecular basis and clinical features of the genetic disorder tuberous sclerosis, which affects approximately 50,000 people in the US alone. Special focus is placed on novel insights into the signal transduction pathways affected by the disease as well as genotype phenotype correlations, while existing and potential therapies are also discussed in depth. The editors are leading experts in research and treatment of the disease as well as the Vice President of the Tuberous Sclerosis Alliance, the only voluntary health organization for TSC in the US.
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In one convenient source, this book provides a broad, detailed, and cohesive overview of seizure disorders and contemporary treatment options. For this Fifth Edition, the editors have replaced or significantly revised approximately 30 to 50 percent of the chapters, and have updated all of them. Dr. Wyllie has invited three new editors: Gregory Cascino, MD, FAAN, at Mayo Clinic, adult epileptologist with special expertise in neuroimaging; Barry Gidal, PharmD, at University of Wisconsin, a pharmacologist with phenomenal expertise in antiepileptic medications; and Howard Goodkin, MD, PhD, a pediatric neurologist at the University of Virginia. A fully searchable companion website will include the full text online and supplementary material such as seizure videos, additional EEG tracings, and more color illustrations.
This Gold Standard in clinical child neurology presents the entire specialty in the most comprehensive, authoritative, and clearly written fashion. Its clinical focus, along with relevant science, throughout is directed at both the experienced clinician and the physician in training. New editor, Dr. Ferriero brings expertise in neonatal neurology to the Fourth Edition. New chapters: Pathophysiology of Hypoxic Ischemic Encephalopathy, Congenital Disorders of Glycosylation, Pediatric Neurotransmitter Diseases, Neurophysiology of Epilepsy, Genetics of Epilepsy, Pediatric Neurorehabilitation Medicine, Neuropsychopharmacology, Pain and Palliative Care Management, Ethical Issues in Child Neurology
Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.
Written by two mothers who have children on the Ketogenic diet, Fighting Back with Fat provides essential information to educate parents on the diets, as well as gives advice to parents to navigate the emotional minefields that often come with attempting these diets. Common stress factors such as fear of failure, hyperresponsibility, dealing effectively with a child's non-compliance, and educating non-supportive relatives, friends and peers, are all addressed in heart-to-heart frankness from mothers who have covered the territory personally. The authors include first-person accounts of the successes and trails of other families as well as a rare glimpse of what kids think of the diets, in their own words. The book closes with the KetoCalculator 101, with tips and advice from the Charlie Foundation's Beth Zupec-Kania, RD, CD, the Keto Calculator's creator and a recipe section offering simple, delicious recipes organized by age group, each with "Keto Bites," fun food facts or practical advice that correspond to each recipe.
The essays in this volume ask what if anything survives of our everyday understanding of the responsible agent once we have decomposed the conscious will and sacked the central executive? Book jacket.
New tools for early detection of cognitive brain diseases like depression, epilepsy, parkinson’s disease etc.and the design, analysia, application of such tools. Immense technical value, novelty, importance of work which is valuable for researchers. Incorporates recent technology - breakthrougha in treating brain disease patients.