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Rapid progress in the definition of tumor antigens, and improved immunization methods, bring effective cancer vaccines within reach. In this wide-ranging survey, leading clinicians and scientists review therapeutic cancer vaccine strategies against a variety of diseases and molecular targets. Intended for an interdisciplinary readership, their contributions cover the rationale, development, and implementation of vaccines in human cancer treatment, with specific reference to cancer of the cervix, breast, colon, bladder, and prostate, and to melanoma and lymphoma. They review target identification, delivery vectors and clinical trial design. The book begins and ends with lucid overviews from the editors, that discuss the most recent developments.
While it is well established that the worldwide pandemic of overweight and obesity has profound effects on promoting cancer, it is now recognized that an alternative aspect of energy balance, namely physical activity and exercise have significant beneficial effects on all aspects of cancer across the spectrum from prevention through treatment and extending through survivorship. Moreover, salutary effects of physical activity and exercise extend across the age span from youth to old age and occur at all stages of cancer extending into palliative care. While the effect of physical activity and exercise on cancer may be partially mediated through obesity control, it is clear that conside...
Recent progress in fundamental tumor immunology has led to immunotherapy trials in patients with solid tumors and hematological malignancies. In the past, immunotherapy approaches were primarily based on enhancement of tumor immunity with cytokines and adjuvant therapy, without knowledge of relevant tumor antigens. The discovery of tumor antigens c
Daniel Thomas was 17 when he was diagnosed with rare bone cancer. His chances of survival were slim. But his father David refused to give up hope and did everything in his power to find his son a cure. Sadly, Daniel didn't survive but this account of the journey is testament to a parent's unconditional love and mankind's desperate need for hope.
The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics including NY-ESO-1: review of an immunogenic tumor antigen; Order, disorder, death: lessons from a superorganism; Control of differentiation in progression of epithelial tumors; Cancer vaccines: preclinical studies and novel strategies; Clinical results of vaccine therapy for cancer: learning from history for improving the future; Immunodominance and immunodomination: critical factors in developing effective CD8+ T-cell based cancer vaccines; NK cell receptors as tools in cancer immunotherapy; Innate immune recognition and suppression of tumors; Inhibitors of the HSP90 molecular chaperone: current status.
Schneeweisz neemt ons in De jacht mee in de sensatie van het jagen. Hij schetst een historisch portret van de jacht en gaat op zoek naar de waarde die de jagerstraditie nog heeft in de 21e eeuw. In ‘De jacht’ neemt Oswin Schneeweisz, een ervaren jager, de lezer mee het veld in en laat hem delen in de sensatie van het jagen. Daarnaast schetst hij een historisch portret van de jacht en gaat hij op zoek naar de waarde die de jagerstraditie nog heeft in de eenentwintigste eeuw. De praktijk van het jagen blijkt veel minder zwart-wit dan voor- en tegenstanders willen doen geloven. ‘De jacht’ is een prikkelende, beschouwende bijdrage aan de discussie over dierenrechten, dierenactivisme en bio-industrie, en de plaats van de mens in de natuur. Schneeweisz gaat daarbij geen controversiële standpunten uit de weg.
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