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Edited by two of the experts in the field, the central aim is to show organic chemists working in process development that enantioselective catalysis is suitable for the large-scale production of enantioenriched intermediates. In so doing, it is equally a source of information and inspiration for academic research, and, with its contribution by Noble prizewinner W. S. Knowles, will also heighten the status of industrial catalyst specialists working in the exciting field of enantioselective catalysis. Some 25 contributions from top industrial researchers around the world present case studies on the development of the widest possible range of large-scale enantioselective processes, featuring stereoselective production processes of fine-chemicals, agrochemicals and pharmaceuticals. Clearly structured according to the nature of the task, this handbook adopts a problem-driven approach such that readers can easily find how colleagues have dealt with a similar situation.
A bundle of books #7 (LEFT TO LAPSE), #8 (LEFT TO VANISH), and #9 (LEFT TO HUNT) in Blake Pierce’s Adele Sharp Mystery series! This bundle offers books seven, eight, and nine in one convenient file, with over 150,000 words of reading. In LEFT TO LAPSE, when a body turns up on a high-speed train passing through France, Germany and Italy—clearly the work of a serial killer—authorities wonder: whose jurisdiction is it? FBI Special Agent Adele Sharp—triple agent of the U.S., France and Germany—is called in as the only one capable of maneuvering the layers of authority and of tapping her brilliant mind to stop the killer. But as more victims turn up—on other trains, in other countries...
In two often neglected passages of the Critique of Pure Reason, Kant submits that the Critique is a 'treatise' or a 'doctrine of method'. These passages are puzzling because the Critique is only cursorily concerned with identifying adequate procedures of argument for philosophy. In this book, Gabriele Gava argues that these passages point out that the Critique is the doctrine of method of metaphysics. Doctrines of method have the task of showing that a given science is indeed a science because it possesses 'architectonic unity' – which happens when it realizes the 'idea' of a science. According to Gava's novel approach, the Critique establishes that metaphysics is capable of this unity, and his reading of the Critique from this perspective not only illuminates the central role of the Transcendental Doctrine of Method within it, but also clarifies the relationship between the different parts of the work.
The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics. Covering cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery, this resource offers an overview of the main routes in therapeutics. Researchers across biochemistry, pharmaceutical, molecular biology, cell biology, immunology, chemistry and biotechnology fields will find this publication invaluable for peptide and protein laboratory research. - Discusses the most recent data, ideas and concepts - Presents case studies and an industrial perspective - Details information from the molecular level to bioprocessing - Thought provoking, for the novice to the specialist - Timely, for today's biopharmaceuticals market
Imre Lakatos (1922-1974) was one of the protagonists in shaping the "new philosophy of science". More than 25 years after his untimely death, it is time for a critical re-evaluation of his ideas. His main theme of locating rationality within the scientific process appears even more compelling today, after many historical case studies have revealed the cultural and societal elements within scientific practices. Recently there has been, above all, an increasing interest in Lakatos' philosophy of mathematics, which emphasises heuristics and mathematical practice over logical justification. But suitable modifications of his approach are called for in order to make it applicable to modern axiomat...
A thorough study of why Kant developed the concept of autonomy, one of his central legacies for contemporary moral thought.
This book describes the essential steps in the development of biocatalytic processes from concept to completion. It is a carefully integrated text which combines the fundamentals of biocatalysis with technological experience and in-depth commercial case studies. The book starts with an introductory look at the characteristics and present applications of biocatalysts, followed by more detailed overviews of these areas.
How are artificial intelligence (AI) and the strong claims made by their philosophical representatives to be understood and evaluated from a Kantian perspective? Conversely, what can we learn from AI and its functions about Kantian philosophy’s claims to validity? This volume focuses on various aspects, such as the self, the spirit, self-consciousness, ethics, law, and aesthetics to answer these questions.
A bundle of books #7 (LEFT TO LAPSE) and #8 (LEFT TO VANISH) in Blake Pierce’s Adele Sharp Mystery series! This bundle offers books seven and eight in one convenient file, with over 100,000 words of reading. In LEFT TO LAPSE, when a body turns up on a high-speed train passing through France, Germany and Italy—clearly the work of a serial killer—authorities wonder: whose jurisdiction is it? FBI Special Agent Adele Sharp—triple agent of the U.S., France and Germany—is called in as the only one capable of maneuvering the layers of authority and of tapping her brilliant mind to stop the killer. But as more victims turn up—on other trains, in other countries—the case grows increasin...