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This book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc.
This book presents the role of nanoparticles in cancer therapy, emphasizing their innovative applications across treatment, diagnosis and the development of therapeutic strategies. The first section of the book describes the applications of nanoparticles in cancer vaccines and gene therapy. It features discussions on polymeric nanoparticles as nanovaccine carriers, membrane-based nano-vaccines for immunotherapy and gene therapy techniques employing nanoparticles. The second section presents advanced nanomedicine approaches, specifying the role of chemodynamic nanoparticles in cancer theranostics, the application of low-dimensional nanomaterials and emerging strategies against drug resistance...
GlobalSoilMap: Basis of the global spatial soil information system contains contributions that were presented at the 1st GlobalSoilMap conference, held 7-9 October 2013 in Orléans, France. These contributions demonstrate the latest developments in the GlobalSoilMap project and digital soil mapping technology for which the ultimate aim is to produce a high resolution digital spatial soil information system of selected soil properties and their uncertainties for the entire world. GlobalSoilMap: Basis of the global spatial soil information system aims to stimulate capacity building and new incentives to develop full GlobalSoilMap products in all parts of the world.
Transience is an exploration into Estelle Asmodelle's neo-abstract expressionism and a journey into perception of form and structure through abstraction. Transience resists discrete interruption but facilitates the observer with interplay between conscious and sub-conscious interpretation of primal symbolism.
John Connerly lived in Johnston County, N.C. He married Kesiah Herring. Their son, Cullen, was born ca. 1745. He married Letitia Ward. Their descendants are scattered throughout the U.S.