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Extracellular purines and pyrimidines (ATP, ADP, UTP and adenosine) are released into the extracellular milieu in response to a variety of stress conditions and act as important regulators of vascular homeostasis. This new book is uniquely focused on the signaling actions of extracellular purines in endothelial cells and the crucial role of extracellular purines in regulation of angiogenesis, vascular tone, cell permeability, wound healing, inflammation and cell-to-cell communication. This book examines the responses of endothelial cells, originating from various tissues (such as cornea, pancreas and uterus), to extracellular nucleotides and adenosine under physiological and pathological con...
The Pulmonary Endothelium is a uniquely comprehensive compendium of our current knowledge of the pulmonary endothelium and is the first book dedicated specifically to the subject, offering insights into current and future approaches to management. The text provides the clinician with the most up-to-date information on one of the core physiological processes in airway disease and is an ideal point of reference for both postgraduates and professionals – specialist physicians in pulmonology and allergy and workers in biomedical and pharmaceutical research.
This book provides the framework for a singular reference in the field of pulmonary hypertension. Pulmonary vascular disease is a complex and heterogeneous condition characterized by remodeling of distal pulmonary arterioles that increases pulmonary vascular resistance to affect cardiopulmonary hemodynamic and right ventricular function adversely, resulting in a clinical syndrome of diminished exercise tolerance, shortness of breath, and heart failure-associated morbidity and mortality. Owing to the availability of novel pulmonary circulation-selective pharmacotherapies over the previous decade, the number of pulmonary hypertension patients eligible for treatment has increased substantially....
Abstracts of XXII International Scientific and Practical Conference
MBC online publishes papers that describe and interpret results of original research conserning the molecular aspects of cell structure and function.
This book aims to identify the most important political, socio-economic, and technical determinants of Internet development in China, through a historical approach that combines political economy, cultural, and public studies. Firstly, the book looks at the most important strategies that compelled the Chinese government to invest in the construction of the Internet infrastructure. Secondly, it examines the relationships between the development of the Internet in China and the emergence of a nascent civil society. Finally, attention is given to three different Chinese online platforms in three different historical periods. This three-pronged approach presents a coherent set of analyses and case studies which are committed to the investigation of the complex process of change undergone by Internet development in China.
In the late 18th and early 19th centuries, attitudes toward history and national identity fostered a romantic rediscovery of folk and fairy tales. This is the period of the Golden Age of folk and fairy tales, when European folklorists sought to understand and redefine the present through the common tales of the past, and long neglected stories became recognized as cultural treasures. In this rich collection, distinguished expert of fairy tales Jack Zipes continues his lifelong exploration of the story-telling tradition with a focus on the Golden Age. Included are one hundred eighty-two tales--many available in English for the first time--grouped into eighteen tale types. Zipes provides an en...
Tissue Repair, Contraction and the Myofibroblast summarizes the latest findings concerning the biology of the myofibroblast, a cell involved in the evolution and contraction of granulation tissue and of fibrotic changes. Coverage shows that the myofibroblast is responsible for the development of hypertrophic scars, pulmonary and renal fibrosis and bronchial asthma. Reviews the cell biology and pathology of the myofibroblast as well as mechanisms of fibrosis evolution in many organs and tissues.