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Environmental Aspects of Trace Elements in Coal
Happy he who could learn the causes of things (Virgil, Georgics 11) There is clearly a place for a book on the environmental aspects of trace elements in coal, especially with the increasing use of coal for power production. Our aim is to provide relevant background information and to update the situation regarding trace elements during beneficiation, combustion, .atmospheric deposition, leaching from wastes anti reclamation. The outcome is a balanced account of the overall situation. The initial chapter gives the rationale behind the planning of the book and puts the topics into the context of trace elements in the environment, while the final chapter summarises the subject matter and concl...
Bulletin
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Introduction to Microfluidics
The second edition of Introduction to Microfluidics captures all the new exciting developments in the field of microfluidics over the last twenty years. While maintaining the same clear structure, and accessible explanations of the basic theory, this new edition is a complete revision of the first edition and makes use of the considerable data collected in the field over the last two decades. The book describes the applications, the market, and attempts to envision the future of microfluidics. It covers the physics of miniaturization, the hydrodynamics of microfluidics in channels and with droplets, transport phenomena in microsystems, electrokinetic phenomena, and an introduction to microfabrication. The basic principles are explored in depth and with rigor, and their main applications are clearly presented. Many examples are provided and discussed simply, most often from a physical perspective, and the book includes 415 figures and 600 references. Offering a cross-disciplinary view of the field embracing biological, chemical, physical and engineering perspectives, this book is an ideal resource for students and researchers at any level.
Metabolism and Epigenetic Regulation: Implications in Cancer
Metabolic programs of individuals are key determinants for disease susceptibility and immune response. This book, edited by experts in the field, summarizes epigenetic signaling pathways that regulate metabolic programs associated with cancer and cancer-related secondary diseases. The first part of the book highlights key metabolic pathways that are implicated in cancer and provides a comprehensive overview on the carbohydrate, protein, lipid, amino- and nucleic acid metabolic pathways that are deregulated in cancer. Special attention is paid to the altered tumor micro-environment that is influenced by the metabolic milieu. Furthermore, the fundamental relationship between the cellular metab...
Activity report
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Genome Editing in Cardiovascular and Metabolic Diseases
This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing. Genome editing is a genetic engineering technique precisely modified specific target genes of organism genome, which has been applied to basic theoretical research and production applications from plants and animals to gene therapy of human beings. Cardiovascular and metabolic diseases have become major factors affecting human health worldwide. This book contains information about bioinformatics, genome editing in cardiovascular diseases, genome editing in metabolic diseases and therapeutic effects. It will be useful for biologist, cardiologist, cardiovascular surgeons, endocrinologist, internists, nurses, undergraduate and graduate students in medicine and cell biology and others interested in cardiovascular and metabolic medicine.
Cell Biology and Translational Medicine, Volume 17
Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 17th volume of a continuing series.
Model-Based Control of Flying Robots for Robust Interaction Under Wind Influence
This book addresses the topic of autonomous flying robots physically interacting with the environment under the influence of wind. It aims to make aerial robots aware of the disturbance, interaction, and faults acting on them. This requires reasoning about the external wrench (force and torque) acting on the robot and distinguishing between wind, interactions, and collisions. The book takes a model-based approach and covers a systematic approach to parameter identification for flying robots. The book aims to provide a wind speed estimate independent of the external wrench, including estimating the wind speed using motor power measurements. Aerodynamics modeling is approached in a data-driven fashion, using ground-truth measurements from a 4D wind tunnel. Finally, the book bridges the gap between trajectory tracking and interaction control, to allow physical interaction under wind influence. Theoretical results are accompanied by extensive simulation and experimental results.
Histamine H4 receptor
H4 R is the newest member of the histamine receptor family, which was discovered about twelve years ago. It is considered a very promising drug target. The effort to improve the pharmacokinetic properties of the currently available H4 R ligands is reflected in a steadily growing number of scientific publications and patent applications. Preclinical data strongly confirms the need for novel potent H4 R ligands to explore their therapeutic value in allergy, inflammation, autoimmune disorders, and possibly, cancer. Readers will be provided with extensive knowledge on histamine metabolism, as well as cellular histamine transport, storage and release, effects of histamine and histamine receptor ligands, with particular attention to the H4 R, on inflammatory cells including mast cells, basophils, eosinophils, neutrophils, macrophages, dendritic cells, and T cells. The present knowledge on the regulatory role of histamine and the therapeutic exploitation of histamine receptor ligands in atopic diseases, with emphasis on human and animal models of asthma, allergic dermatitis and pruritus are discussed.
Arctic Geology and Petroleum Potential
Since the search for hydrocarbon resources in the Arctic started in the 1930's the exploration activity has expanded into many of the Arctic regions, and several of the Arctic sedimentary basins have proven to be important sources of hydrocarbon. Nevertheless, the Arctic continental margins and adjacent onshore areas are still largely unexplored in the context of petroleum, and are therefore considered to be one of the few regions in the world where significant undiscovered sources of hydrocarbon may exist. The aim of the book is to give an updated overview of the geology of the Arctic sedimentary basins and their petroleum potential. Although the different basins vary significantly as regar...
