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With the recent increase in the scope of drug and alcohol problems has come an awareness of the need for solutions. In this context, federal support for research on drug problems increased tremendously during the last 10 to 15 years with the establishment of the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Funding from these and other sources has led to a substantial increase in the quantity and quality ofpublished work related to substance abuse. As data accumulate, it is becoming more apparent that substance abuse problems are extremely complex and are influenced by a variety ofbiological psychological, and environmental variab...
A comparison of evolutionary algorithms. Organic evolution and problem solving. Biological background. Evolutionary algorithms and artificial intelligence. Evolutionary algorithms and global optimization. Early approaches. Specific evolutionary algorithms. Evolution strategies. Evolutionary programming. Genetic algorithms. Artificial landscapes. An empirical comparison. Extending genetic algorithms. Selection. Selection mechanisms. Experimental investigation of selection. Mutation. Simplified genetic algorithms. An experiment in meta-evolution. Summary and outlook. Data for the fletcher-powell function. Data from selection experiments. Software. The multiprocessor environment; mathematical symbols.
The European Union is traditionally seen as a new and partly separate legal order within the global legal system. At the same time, the EU is an important player in the global governance network. The strong and explicit link between the EU and a large number of other international organisations raises questions concerning the impact of decisions taken by those organisations and of international agreements concluded with those organisations (either by the EU itself or by its Member States) on the autonomy of the EU legal order. This book addresses the relationship between the EU and other international organisations by looking at the increasing influence of norms enacted by international organisations on the shaping of EU law.
To comment at length on the importance of the benzodiazepines seems superfluous within the scope of this preface. No other class of active substances has experienced an even approximately compa rable advance in the past two decades. It is therefore not surprising that the formerly dominant barbiturates and bromocarbamides have had to give way in many fields to the benzodiazepines, which now rank first (Proudfoot and Park [1828]). Closely linked with the great therapeutic importance of the benzodia zepines are analytical problems. Detection and the determination of blood levels can be necessary under therapeutic aspects, for instance in working out optimally effective levels in the treatment ...
This second volume continues the description of the psychotropic agents and discusses anxiolytics, gerontopsychopharmacological agents, and psychomotor stimulants. Of these groups of substances, most of this volume has been devoted to anxiolytics as the authors have endeavored to convey as complete a picture as possible. The editors are of the opinion that particular attention should be given to anxiolytics with regard to their range of administration as this is the most frequently prescribed group of psychotropic drugs. In contrast to neuroleptics and thymoleptics, anxiolytics are a class of psychotropic drugs whose therapeutic effect can be recognized in animal experiments to some extent. ...