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Building Strategies for Porcine Cancer Models
The eBook "Building Strategies for Porcine Cancer Models" presents a series of articles demonstrating the state-of-the-art developments in pig models for cancer research. Renowned researchers dedicated to the reproduction, genomic and biological engineering of the pig model for biomedicine contribute to this special research area. Although advances in these areas are occurring at surprising speeds, they are still far from realizing all the potential benefits that this biological model could provide to science. The current biomedical models may limit the frontier of knowledge in the cancer research.
Genetics, Evolution, and Conservation of Neotropical Fishes
Fish represent the most ancestral and specious group of vertebrates, and occupy more diverse aquatic environments around the world. Ichthyofauna is extremely diverse, especially in megadiverse countries occupying biogeographical regions such as the Neotropical Region, which covers an extensive area between North and South America. Much of this biodiversity will be extinct, even before science knows any aspect of its biology. Like this, Neotropical fish genetics started in the end of the 70’s with papers studying the chromosomes of Hoplias malabaricus (Family Erythrinidae) and the karyotype variation among three genera of the family Anostomidae. The topic at that time was concentrated in tw...
Advances and Challenges in Nanomedicine
Nanotechnology is a multidisciplinary field that is revolutionizing the way we detect and treat damage to the human body. Nanomedicine applies nanotechnology to highly specific medical interventions for the prevention, diagnosis, and treatment of diseases. They are increasingly being used to overcome biological barriers in the body to improve the way we deliver compounds to specific tissues and organs. In particular, nanomedicines have been shown to be beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake, and improving biodistribution of compounds to target sites in vivo. Nanomedicines have demonstrated significant therapeutic advantages for a ...
Biotecnologia aplicada à saúde - vol. 2
Nesta coleção a intenção foi reunir, em uma obra didática, sucinta e objetiva, os fatos mais recentes na literatura com os conhecimentos clássicos dos temas disponíveis em obras separadas. Para se ter todo o escopo de Biotecnologia Aplicada à Saúde e Biotecnologia Aplicada à Agro&Indústria, dividimos o primeiro tema em três volumes e o segundo em um, totalizando 4 volumes, sendo que todos os tópicos são abordados nos cursos de pós-graduação em Biociências e Biotecnologia, dentre outros. Seguindo essa direção e no sentido de produção de um livro que seja para o uso tanto de alunos de graduação como de pós-graduação e para aqueles profissionais que queiram se introdu...
Inflammation and Immunity in Depression
Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contr...
Handbook of the Fundamentals of Financial Decision Making
This handbook in two parts covers key topics of the theory of financial decision making. Some of the papers discuss real applications or case studies as well. There are a number of new papers that have never been published before especially in Part II.Part I is concerned with Decision Making Under Uncertainty. This includes subsections on Arbitrage, Utility Theory, Risk Aversion and Static Portfolio Theory, and Stochastic Dominance. Part II is concerned with Dynamic Modeling that is the transition for static decision making to multiperiod decision making. The analysis starts with Risk Measures and then discusses Dynamic Portfolio Theory, Tactical Asset Allocation and Asset-Liability Manageme...
"Gorgias" and "Phaedrus"
With a masterful sense of the place of rhetoric in both thought and practice and an ear attuned to the clarity, natural simplicity, and charm of Plato's Greek prose, James H. Nichols Jr., offers precise yet unusually readable translations of two great Platonic dialogues on rhetoric. The Gorgias presents an intransigent argument that justice is superior to injustice: To the extent that suffering an injustice is preferable to committing an unjust act. The dialogue contains some of Plato's most significant and famous discussions of major political themes, and focuses dramatically and with unrivaled intensity on Socrates as a political thinker and actor. Featuring some of Plato's most soaringly ...
Chemical Epigenetics
This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology. The book also covers the design, synthesis and biological validation of epigenetic chemical modulators, which can be useful as novel chemotherapeutic agents. Particular attention is given to the chemical mechanisms of action of these molecules and to the drug discovery prose which allows their identification. This book will appeal to students who want to know the extensive progresses made by epigenetics (targets and modulators) in the last years from the beginning, and to specialized scientists who need an instrument to quickly search and check historical and/or updated notices about epigenetics.
Human Interaction and Emerging Technologies
This book reports on research and developments in human-technology interaction. A special emphasis is given to human-computer interaction, and its implementation for a wide range of purposes such as healthcare, aerospace, telecommunication, and education, among others. The human aspects are analyzed in detail. Timely studies on human-centered design, wearable technologies, social and affective computing, augmented, virtual and mixed reality simulation, human rehabilitation and biomechanics represent the core of the book. Emerging technology applications in business, security, and infrastructure are also critically examined, thus offering a timely, scientifically-grounded, but also profession...
