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Extrasynaptic transmission is a unifying term for a wide variety of cellular processes, in which outside of synaptic terminals transmitter substances activate extrasynaptic receptors. Whereas “synaptic transmission” immediately refers to a process occurring at nerve terminals in which the arrival of a presynaptic impulse evokes exocytosis followed by a postsynaptic response within a millisecond time scale, extrasynaptic transmission has a wide diversity of ultrastructural and therefore mechanistic associated phenomena. In comparison to synaptic, extrasynaptic exocytosis may last for seconds or even minutes, thus expanding the timing of neuronal signaling. Extrasynaptic transmission has n...
Including some of the newest advances in the field of neurophysiology, this book can be considered as one of the treasures that interested scientists would like to collect. It discusses many disciplines of clinical neurophysiology that are, currently, crucial in the practice as they explain methods and findings of techniques that help to improve diagnosis and to ensure better treatment. While trying to rely on evidence-based facts, this book presents some new ideas to be applied and tested in the clinical practice. Advances in Clinical Neurophysiology is important not only for the neurophysiologists but also for clinicians interested or working in wide range of specialties such as neurology, neurosurgery, intensive care units, pediatrics and so on. Generally, this book is written and designed to all those involved in, interpreting or requesting neurophysiologic tests.
A timely overview covering the three major types of glial cells in the central nervous system - astrocytes, microglia, and oligodendrocytes. New findings on glia biology are overturning a century of conventional thinking about how the brain operates and are expanding our knowledge about information processing in the brain. The book will present recent research findings on the role of glial cells in both healthy function and disease. It will comprehensively cover a broad spectrum of topics while remaining compact in size.
The term “synaptic plasticity” is a broad concept, which is studied with a variety of experimental approaches. One focus is the impact of changes in synaptic, neuronal and glial morphology on brain circuitry and behavior. In this regard, unique animal models have been key to the study of affective and social behaviors and neurological and psychiatric diseases. However, there is a paucity of compilations directed toward the correlation of alterations in synaptic structure with various physiological and behavioral paradigms. This Frontiers Research Topic will, therefore, serve as an exciting forum for the exchange of novel hypotheses and data and an important resource and reference for investigators studying synaptic and brain plasticity, as well as those in related fields.
A comprehensive overview of the many factors that can influence brain plasticity throughout the lifespan. Addresses perinatal plasticity, functional state plasticity, injury-induced plasticity, and stressor-induced plasticity. Because it looks at so many aspects of the field, this volume will serve as a great resource for students as well as researchers interested in expanding their knowledge. The volume comes out as an integrated view based in the expertise of Ibero American neuroscientists working in the field.