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Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects suggests novel theoretical tools to test and evaluate drug interactions seen with combinatorial drug therapy. The book provides an in-depth, yet controversial, exploration of existing tools for analysis of dose-response studies at equilibrium or steady state. The book is recommended reading for post-graduate students and researchers engaged in the study of systems biology, networks, and the pharmacodynamics of natural or industrial drugs, as well as for medical clinicians interested in drug application and combinatorial drug therapy. Even people without mathematical skills will be able to follow the pros and cons of reaction schemes and their related distribution equations. Chapter 9 is a hands-on guide for software to plot, fit and analyze one’s own data.
This critical and inclusive edited collection offers an overview of the musical in relation to issues of race, culture and identity. Bringing together contributions from cultural, American and theatre studies for the first time, the chapters offer fresh perspectives on musical theatre history, calling for a radical and inclusive new approach. By questioning ideas about what the musical is about and who it for, this groundbreaking book retells the story of the musical, prioritising previously neglected voices to reshape our understanding of the form. Timely and engaging, this is required reading for undergraduate and postgraduate students of musical theatre. It offers an intersectional approach which will also be invaluable for theatre practitioners.
How can a song help the hungry and persecuted to survive? Stephanie Sieburth's Survival Songs explores how a genre of Spanish popular music, the copla, as sung by legendary performer Conchita Piquer, helped Republican sympathizers to survive the Franco regime's dehumanizing treatment following the Spanish Civil War (1936-39). Piquer's coplas were sad, bitter stories of fallen women, but they offered a way for the defeated to cope with chronic terror, grief, and trauma in the years known as the "time of silence." Drawing on the observations of clinical psychotherapy, Sieburth explores the way in which listening to Piquer's coplas enabled persecuted, ostracized citizens to subconsciously use music, role-play, ritual, and narrative to mourn safely and without fear of repercussion from the repressive state. An interdisciplinary study that includes close readings of six of Piquer's most famous coplas, Survival Songs will be of interest to specialists in modern Spanish studies and to clinical psychologists, musicologists, and those with an interest in issues of trauma, memory, and human rights.
After the success of The Northern Clemency, shortlisted for the 2008 Man Booker Prize, Philip Hensher brings us another slice of contemporary life, this time the peaceful civility and spiralling paranoia of a small English town.
A chess match seems about as solitary an endeavor as there is in sports: two minds, on their own, in fierce opposition. But is this the case? Inevitably these two minds are in dialogue, and perhaps might be better understood as partners in play. And surrounding that one-on-one contest is a community life that can be as dramatic and intense as the across-the-board confrontation. Gary Alan Fine has spent years immersed in several communities of amateur and professional chess players--children and adults--and in Players and Pawns he takes readers deep inside these worlds, revealing a complex, brilliant, feisty world of commitment and conflict. Opening with a close look at a routine, yet financi...
Analytical Pyrolysis: Techniques and Applications provides an overview of analytical pyrolysis applied to geochemistry, biology, polymers, and biomass. This book presents a survey of basic phenomena, data analysis, and instrumentation. Organized into 15 chapters, this book begins with an overview of mass spectrometry in developing ion sources that are applicable to materials that either have low volatility, high molecular weight, are thermally unstable or some combination of the three. This text then examines the role of thermal processes in many of the desorption methods. Other chapters consider desorption techniques, which are closely allied to analytical pyrolysis. This book discusses as well the Flash Vacuum Pyrolysis/Field Ionization Mass Spectrometry (FVP/FIMS) technique, which is based on a direct link between the pyrolysis unit and a double focusing mass spectrometer. The final chapter deals with inert atmosphere poly (vinyl chloride) (PVC) thermal decomposition. This book is a valuable resource for chemists and researchers.
A practical guide to, and history of, musical theatre. What makes the great shows work, and why some never did.