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Viscoelastic Interfaces Driven in Disordered Media
This book offers an in-depth study of two well-known models of “avalanche” dynamics, modified minimally by the inclusion of relaxation. Many complex systems respond to continuous inputs of energy by accumulation of stress over time, interrupted by sudden energy releases called avalanches. The first model studied is the viscoelastic interface driven over disorder, which is shown to display the fundamental features of friction. In the mean-field limit, the friction force derived semi-analytically is compatible with laboratory experiments (displaying both velocity weakening and contact aging). In two dimensions, large-scale numerical simulations are in good agreement with the basic features of real earthquakes (Gutenberg-Richter Law, aftershock migration). The second model is a non-Markovian variant of Directed Percolation, in which we observe that the universality class is only partly modified by relaxation, a promising finding with respect to our first model.
The Societal Foundations of National Competitiveness
Nations rise and fall, succeed or fail in rivalries, and enjoy stability or descend into chaos because of a complex web of factors. One critical component is a nation’s essential social characteristics. This report examines the characteristics of highly competitive societies, explores the relationship of a nation’s social condition to its global standing, and then applies these lessons to the United States today.
Caveolins and Caveolae
Caveolae are 50-100 nm flask-shaped invaginations of the plasma membrane that are primarily composed of cholesterol and sphingolipids. Using modern electron microscopy techniques, caveolae can be observed as omega-shaped invaginations of the plasma membrane, fully-invaginated caveolae, grape-like clusters of interconnected caveolae (caveosome), or as transcellular channels as a consequence of the fusion of individual caveolae. The caveolin gene family consists of three distinct members, namely Cav-1, Cav-2 and Cav-3. Cav-1 and Cav-2 proteins are usually co-expressed and particularly abundant in epithelial, endothelial, and smooth muscle cells as well as adipocytes and fibroblasts. On the other hand, the Cav-3 protein appears to be muscle-specific and is therefore only expressed in smooth, skeletal and cardiac muscles. Caveolin proteins form high molecular weight homo- and/or hetero-oligomers and assume an unusual topology with both their N- and C-terminal domains facing the cytoplasm.
Le Courier François
None
Women, Work and Family
Women, Work and Family is a classic of women's history and is still the only text on the history of women's work in England and France, providing an excellent introduction to the changing status of women from 1750 to the present.
Colonial Frontiers
This wide-ranging collection explores the formation, structure, and maintenance of boundaries and frontiers in settler colonies. Looking at cross-cultural interactions in the settler colonies of Australia, New Zealand, South Africa, and America. the contributors illuminate the formation of new boundaries and the interaction between settler societies and indigenous groups.
Lipid A in Cancer Therapy
Cancer remains a major challenge for modern society. Not only does cancer rank among the first three causes of mortality in most population groups but also the therapeutic options available for most tumor types are limited. The existing ones have limited efficacy, lack specificity and their administration carry major side effects. Hence the urgent need for novel cancer therapies. One of the most promising avenues in research is the use of specific immunotherapy. The notion that the immune system may have important anti-tumor effects has been around for more than a century now. Every major progress in microbiology and immunology has been immediately followed by attempts to apply the new knowl...
François Mauriac
Examines aspects of Mauriac's work and career that have been unduly neglected and suggests new critical approaches.
