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This manual has been compiled in response to the rapid expansion of instrumented spinal surgery using minimally invasive and non-fusion techniques, with a view to meeting the needs of spinal surgeons (orthopaedic and neurosurgeons). The various open, less invasive, and minimally invasive techniques are presented step by step in a clear and instructive way with the aid of more than 600 high-quality illustrations. Careful attention is paid to all aspects vital to the success of any spinal operation: precise definition of indications and contraindications, technical and organizational factors, good operating technique, and correct preoperative preparation and positioning of the patient. This second edition of the manual takes full account of the latest developments in spinal instrumentation and implants and new surgical techniques. It is authoritative, concise, and portable – ideal for use in a fast-paced clinical setting – and will serve as a daily companion for spinal surgeons and others who care for patients with spinal disorders.
There are many human cancers which actively synthesize specific characteristic proteins such as melanomas, thyroid cancer and squamous cell carcinoma. Many cancer researchers have of course tried to utilize this specific activity as a key for the selective treatment of cancers. In the past for example, the molecular hybrid compound of DOPA, a substrate of melanin, and nitrogen mustard N-oxide hydrochloride, a ctyotoxic anti-tumor drug, was synthesized as Melphalan and used to treat malignant melanoma. A major problem arose though in that it was soon found to be highly suppressive toward bone marrow and quite toxic while not being remarkably effective. Thus, malignant melanoma could not be cu...
Frontiers in Neutron Capture Therapy contains current research results originally presented at the Eighth International Symposium on Neutron Capture Therapy for Cancer in La Jolla, CA. This comprehensive collection of peer-reviewed manuscripts is showcased in two volumes covering all aspects of the development of this multidisciplinary approach to cancer therapy. Volume I of this work includes clinical results and current progress in treatment planning, neutron sources and dosimetry, while Volume II presents the synthesis, pharmacology and tissue-targeting design of boron compounds, including work on preclinical dosimetry and radiobiology. Intended for researchers and clinicians involved with or interested in new modes of cancer therapy, this volume will also serve as a useful guideline for scientists, students, and practitioners in the field.
Don’t miss it! The second, completely revised and expanded edition of the successful surgical manual on minimally invasive spine surgery includes 51 chapters (including more than 20 new chapters) covering all current minimally invasive techniques in spine surgery. A complete survey of all microsurgical and endoscopic techniques with a special focus on semi-invasive injection techniques for diagnostic and therapeutic purposes in low back pain is given. The clear chapter structure with terminology, history, surgical principles, advantages/disadvantages, indications, access principles, complications, and results facilitates navigation through the manual. Topics include the principles of microsurgical and endoscopic treatment, spinal navigation and computer-assisted surgery, minimally invasive reconstruction, fusion, dynamic stabilization in fractures, degenerative disc disease, spinal stenosis, low back pain and deformities. The didactic presentation of surgical steps makes the reader familiar with all types of new minimally invasive techniques in clinical use or still in ongoing clinical trials such as minimally invasive spine arthroplasty.
Ausgewiesene Fachkompetenz für alle Wirbelsäulenerkrankungen „Wirbelsäule interdisziplinär“: die gebündelte Expertise von Neurochirurgen, Orthopäden und Unfallchirurgen – auf Basis des Curriculums der Deutschen Wirbelsäulengesellschaft. Renommierte Spezialisten beleuchten die wesentlichen Krankheitsbilder und Verletzungen der Wirbelsäule inklusive Diagnostik und Therapieoptionen. Das Spektrum der Eingriffe reicht von klassisch offenen über modernste minimalinvasive, endoskopisch assistierte, navigationsgestützte bis hin zu mikrochirurgischen OP-Techniken. Detailliert und reich bebildert geht das evidenzbasierte Werk auf Instrumentarien, Zugänge, Techniken und Implantat-Typen...
This book offers essential guidance on selecting the most appropriate surgical management option for a variety of spinal conditions, including idiopathic problems, and degenerative disease. While the first part of the book discusses the neuroanatomy and biomechanics of the spine, pain mechanisms, and imaging techniques, the second guides the reader through the diagnostic process and treatment selection for disorders of the different regions of the spine, based on the principles of evidence-based medicine. I.e., it clearly explains why a particular technique should be selected for a specific patient on the basis of the available evidence, which is carefully reviewed. The book identifies potential complications and highlights technical pearls, describing newer surgical techniques and illustrating them with the help of images and accompanying videos. Though primarily intended for neurosurgeons, the book will also be of interest to orthopaedic surgeons, specialists in physical medicine, and pain specialists.
Handbook of Spine Surgery, Second Edition, is a completely updated and comprehensive reference that distills the basic principles of contemporary spine surgery. Its coverage of both principles and techniques makes it an excellent refresher before surgery or a valuable daily companion for residents and surgeons caring for patients with spinal disorders. Key Features of the Second Edition: New chapters on adult degenerative deformity, pediatric scoliosis and radiographic principles of deformity Expanded spinal trauma section now includes separate chapters on cervical, thoracolumbar, and sacropelvic injuries Common clinical questions (with answers) at the end of each chapter highlight topics frequently encountered in the operating room and on board exams Easy-to-read bulleted format The second edition of this handbook is the go-to guide for all those involved in spine surgery.
Better understanding of biomechanics, improvements in technology, and new knowledge of the disease process in the spine have led to rapid advances in spinal instrumentation.