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Das Buch enthält die Abstracts der eingeladenen bzw. angenommenen Vorträge der 6. Konferenz der Deutschen Arbeitsgemeinschaft Statistik (DAGStat), welche vom 28. März bis 1. April 2022 am Universitätsklinikum Hamburg-Eppendorf (UKE) in Kooperation mit der Universität Hamburg sowie der Helmut-Schmidt-Universität stattfand. Die Konferenz stellte ebenfalls das 68. Biometrische Kolloquium der Deutschen Region der International Biometric Society (IBS-DR) dar, sowie die 45. Jahrestagung der Gesellschaft für Klassifikation (GfKl/Data Science Society). Die Vorträge behandelten dabei ein breites Spektrum sowohl angewandter als auch eher methodischer/theoretischer Themen aus dem Bereich Statistik und Data Science.
Nowadays the term dose-response is used in many different contexts and many different scientific disciplines including agriculture, biochemistry, chemistry, environmental sciences, genetics, pharmacology, plant sciences, toxicology, and zoology. In the 1940 and 1950s, dose-response analysis was intimately linked to evaluation of toxicity in terms of binary responses, such as immobility and mortality, with a limited number of doses of a toxic compound being compared to a control group (dose 0). Later, dose-response analysis has been extended to other types of data and to more complex experimental designs. Moreover, estimation of model parameters has undergone a dramatic change, from strugglin...
Nachdruck der Originalausgabe von 1888. Julius Schwieters beschreibt in seinem Werk die bäuerlichen Strukturen in den Orten des östlichen Teilen des ehemaligen Kreises Lüdinghausen.
Of Mice and Men ISBN 3-7757-1765-X / 978-3-7757-1765-6 Hardcover, 8 x 11 in. / 344 pgs / 250 color. / U.S. $40.00 CDN $48.00 August / Art
Um die Bewertung von KMU für Zwecke der Erbschaftsteuer zu erleichtern hat der Gesetzgeber ein vereinfachtes Kapitalwertkalkül,das sog. vereinfachte Ertragswertverfahren gemäß § 199 ff. BewG, entwickelt. Damit soll dem Steuerpflichtigen eine einfache Bewertung des Unternehmens ermög-licht werden. Wesentliche Vereinfachungen betreffen dabei sowohl den Zähler als auch den Nen-ner des Kapitalwertkalküls. So wird etwa die Zählergröße als durchschnittlicher Jahresertrag aus Vergangenheitsdaten abgeleitet. Im Nenner wird ebenfalls durch die Vorgabe des Risikozuschlages von 4,5 % eine pauschalierende Typisierung vorgenommen. Die verfasste Arbeit setzt sich daher zum Ziel, empirisch festzustellen, ob und inwieweit eine „richtige“ Bewertung durch das verein-fachte Ertragswertverfahren erreicht wird.
Part 7: Contains results of U.S. Government investigation of German-based I.G. Farben international cartel organization and activities in support of Nazi and possible future German military efforts
Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
This classic textbook builds theoretical statistics from the first principles of probability theory. Starting from the basics of probability, the authors develop the theory of statistical inference using techniques, definitions, and concepts that are statistical and natural extensions, and consequences, of previous concepts. It covers all topics from a standard inference course including: distributions, random variables, data reduction, point estimation, hypothesis testing, and interval estimation. Features The classic graduate-level textbook on statistical inference Develops elements of statistical theory from first principles of probability Written in a lucid style accessible to anyone wit...
This book is the first to provide balanced examination of both pediatric liver disease and liver transplantation – two topics that are inherently related, given that most chronic liver disorders eventually require organ replacement. The different forms of liver disease encountered in the pediatric age group are first discussed in a series of disease-specific chapters that have a reader-friendly, uniform structure covering pathophysiology, diagnostic and treatment algorithms, clinical cases, and transition to adult care. Key topics in the field of liver transplantation are then addressed. Examples include indications and contraindications, surgical techniques and complications, immunosuppre...